Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: A multicomponent, evidence-based and interdisciplinary Patient Blood Management (PBM) program was introduced at the University Hospital Frankfurt in July 2013. The implementation strategy included practical and tactical components aimed to increase knowledge on the risks of preoperative anemia, to standardize hemotherapy, and to facilitate PBM components.
Methods: This article analyzes barriers to PBM implementation and outlines a strategy to introduce and manifest PBM. The effects in Frankfurt were measured in a before and after questionnaire study distributed among groups of physicians immediately before and 1 year after PBM implementation.
Results: 142 clinicians completed the questionnaire in July 2013 and 101 clinicians in August 2014. Absolute certainty that the treatment of preoperative anemia favorably influences morbidity and mortality rose from 25 to 37%. Transfusion behavior seems to have been affected: In 2014, 56% of clinicians stated that they clinically reassess the patient and analyze hemoglobin following each single red blood cell unit compared to only 38% stating this in 2013.
Conclusion: These results show that our implementation strategy was effective in changing physicians' risk perception, attitude, and knowledge on PBM principles. Our experience highlights key success factors for the implementation of a comprehensive PBM program.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439782 | PMC |
| http://dx.doi.org/10.1159/000380868 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
eHealth and Hypertensive Disorders of Pregnancy: Systematic Review.
J Med Internet Res
September 2025
Faculty of Medicine, The University of Sydney, Sydney, Australia.
Background: Hypertensive disorders of pregnancy (HDP) affect up to 10% of pregnancies and can have adverse short and long-term implications for women and their babies. eHealth interventions include any health service or treatment delivered using the internet and related technology that aims to facilitate, capture, or exchange knowledge. eHealth interventions are increasingly used across many health care settings with improved outcomes.
View Article and Find Full Text PDFKey factors underpinning neuroimmune-metabolic-oxidative (NIMETOX) major depression in outpatients: paraoxonase 1 activity, reverse cholesterol transport, increased atherogenicity, protein oxidation, and differently expressed cytokine networks.
Neuro Endocrinol Lett
September 2025
Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China.
Background: Major depressive disorder (MDD) is associated with neuro-immune - metabolic - oxidative (NIMETOX) pathways.
Aims: To examine the connections among NIMETOX pathways in outpatient MDD (OMDD) with and without metabolic syndrome (MetS); and to determine the prevalence of NIMETOX aberrations in a cohort of OMDD patients.
Methods: We included 67 healthy controls and 66 OMDD patients and we assessed various NIMETOX pathways.
Endoscopic Spring Mediated Cranioplasty for Management of Coronal Craniosynostosis.
J Craniofac Surg
September 2025
Division of Plastic Surgery, Stanford University School of Medicine, Stanford.
Background: Spring-mediated cranioplasty (SMC) is a safe and effective treatment for craniosynostosis. The authors describe the largest cohort of endoscopic SMC for coronal craniosynostosis to date, highlighting the evolution of their technique.
Methods: The authors retrospectively reviewed patients who underwent endoscopic coronal suturectomy and SMC between 2017 and 2023.
A Retrospective Review of Craniosynostosis Reconstruction at a Community Children's Hospital Compared With Academic Centers.
J Craniofac Surg
September 2025
Department of Pediatric Plastic and Reconstructive Surgery, Children's Hospital Colorado.
Background: Craniosynostosis repair is traditionally performed at high-volume academic centers with multidisciplinary teams. Access barriers in rural or suburban regions raise the question of whether comparable outcomes can be achieved and if this surgery can be performed safely in community settings.
Objective: To evaluate the safety and perioperative outcomes of cranial vault reconstruction for craniosynostosis performed at a community-based children's hospital and compare these outcomes to those reported at academic institutions.
Marburg Virus Disease in Rwanda, 2024 - Public Health and Clinical Responses.
N Engl J Med
September 2025
Rwanda Biomedical Center, Kigali.
Background: On September 27, 2024, Rwanda reported an outbreak of Marburg virus disease (MVD), after a cluster of cases of viral hemorrhagic fever was detected at two urban hospitals.
Methods: We report key aspects of the epidemiology, clinical manifestations, and treatment of MVD during this outbreak, as well as the overall response to the outbreak. We performed a retrospective epidemiologic and clinical analysis of data compiled across all pillars of the outbreak response and a case-series analysis to characterize clinical features, disease progression, and outcomes among patients who received supportive care and investigational therapeutic agents.