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Background: This article provides an overview of the first BIOASQ challenge, a competition on large-scale biomedical semantic indexing and question answering (QA), which took place between March and September 2013. BIOASQ assesses the ability of systems to semantically index very large numbers of biomedical scientific articles, and to return concise and user-understandable answers to given natural language questions by combining information from biomedical articles and ontologies.
Results: The 2013 BIOASQ competition comprised two tasks, Task 1a and Task 1b. In Task 1a participants were asked to automatically annotate new PUBMED documents with MESH headings. Twelve teams participated in Task 1a, with a total of 46 system runs submitted, and one of the teams performing consistently better than the MTI indexer used by NLM to suggest MESH headings to curators. Task 1b used benchmark datasets containing 29 development and 282 test English questions, along with gold standard (reference) answers, prepared by a team of biomedical experts from around Europe and participants had to automatically produce answers. Three teams participated in Task 1b, with 11 system runs. The BIOASQ infrastructure, including benchmark datasets, evaluation mechanisms, and the results of the participants and baseline methods, is publicly available.
Conclusions: A publicly available evaluation infrastructure for biomedical semantic indexing and QA has been developed, which includes benchmark datasets, and can be used to evaluate systems that: assign MESH headings to published articles or to English questions; retrieve relevant RDF triples from ontologies, relevant articles and snippets from PUBMED Central; produce "exact" and paragraph-sized "ideal" answers (summaries). The results of the systems that participated in the 2013 BIOASQ competition are promising. In Task 1a one of the systems performed consistently better from the NLM's MTI indexer. In Task 1b the systems received high scores in the manual evaluation of the "ideal" answers; hence, they produced high quality summaries as answers. Overall, BIOASQ helped obtain a unified view of how techniques from text classification, semantic indexing, document and passage retrieval, question answering, and text summarization can be combined to allow biomedical experts to obtain concise, user-understandable answers to questions reflecting their real information needs.
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http://dx.doi.org/10.1186/s12859-015-0564-6 | DOI Listing |
Behav Res Methods
September 2025
Laboratoire de Psychologie, Université de Bordeaux, LabPsy UR 4139, 3 Place de la Victoire, 33076, Bordeaux Cedex, France.
This article presents a new set of semantic feature production norms, collected from 580 young adults, for 360 French concepts across various semantic categories. Although empirically derived feature norms have been developed for several languages and have been shown to be useful for investigating semantic memory and providing assessment tools, none are currently available for native French-speaking populations. In this study, the participants performed a property generation task in which they were asked to list features to describe the characteristics of each given concept (e.
View Article and Find Full Text PDFArq Gastroenterol
September 2025
Escola Superior de Ciências da Saúde, Fundação de Ensino e Pesquisa em Ciências da Saúde, Brasília, DF, Brasil.
Objectives: This study aimed to translate the Neurogenic Bowel Dysfunction Score into Brazilian Portuguese, adapting it culturally and validating it semantically.
Methods: The process followed international guidelines for translation, back-translation, cultural adaptation, and semantic validation, involving a committee of specialists and a pre-test with 10 Brazilian pediatric patients with neurogenic bowel dysfunction (mean age: 11 years). Participants were divided into two groups, depending on whether they used transanal irrigation for intestinal management.
Stud Health Technol Inform
September 2025
Department of Computer Science, Kempten University of Applied Sciences, Kempten, Germany.
Introduction: Manual ICD-10 coding of German clinical texts is time-consuming and error-prone. This project aims to develop a semi-automated pipeline for efficient coding of unstructured medical documentation.
State Of The Art: Existing approaches often rely on fine-tuned language models that require large datasets and perform poorly on rare codes, particularly in low-resource languages such as German.
bioRxiv
August 2025
Ray and Stephanie Lane Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, 15217, US.
Codon sequence design is crucial for generating mRNA sequences with desired functional properties for tasks such as creating novel mRNA vaccines or gene editing therapies. Yet existing methods lack flexibility and controllability to adapt to various design objectives. We propose a novel framework, ARCADE, that enables flexible control over generated codon sequences.
View Article and Find Full Text PDFJ Am Med Inform Assoc
August 2025
Department of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, 27710, United States.
Objectives: Systematic reviews in comparative effectiveness research require timely evidence synthesis. With the rapid advancement of medical research, preprint articles play an increasingly important role in accelerating knowledge dissemination. However, as preprint articles are not peer-reviewed before publication, their quality varies significantly, posing challenges for evidence inclusion in systematic reviews.
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