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http://dx.doi.org/10.4103/0019-5154.152539 | DOI Listing |
J Pediatr Surg
September 2025
Ankara University School of Medicine, Department of Pediatric Surgery, Ankara, Turkey. Electronic address:
Background: Pilonidal sinus disease (PSD) is a common condition in adolescents, often resulting in recurrence, prolonged recovery, and significant discomfort. Although multiple surgical approaches exist, the optimal treatment for pediatric patients remains unclear. This study aimed to compare the short-term outcomes of endoscopic pilonidal sinus treatment combined with platelet-rich plasma application (EPSIT+PRP) and excision with primary closure (EPC) in children and adolescents with PSD.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Periodontology, Faculty of Dentistry, University of Çukurova;
Platelet-Rich Fibrin (PRF) is an autologous matrix rich in platelets, leukocytes, and growth factors that support tissue regeneration. Enhancing its structural and biological properties through biomaterial supplementation may improve clinical outcomes. This study evaluated the effects of adding hyaluronic acid (HA) and collagen to PRF on growth factor release and mechanical strength.
View Article and Find Full Text PDFCrit Care Explor
September 2025
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
Objective: To identify distinct phenotypes of acute respiratory distress syndrome (ARDS) developing after hematopoietic cell transplantation (HCT), using routinely available clinical data at ICU admission.
Design: Multicenter retrospective cohort study using latent class analysis.
Setting: ICUs across three Mayo Clinic campuses (Minnesota, Florida, and Arizona).
Arch Med Res
September 2025
Department of Hematology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China. Electronic address:
Objective: A subset of patients with multiple myeloma (MM) experience early relapse despite the absence of any high-risk features at diagnosis, defined as functional high-risk (FHR) MM with inferior prognosis. This study compared FHR and standard risk (SR) MM cohorts to investigate clinical risk factors and establish a validated prognostic model for early prediction of FHR in patients with MM that were transplanted.
Methods: A retrospective cohort study was conducted to analyze the clinical data of patients with MM.
Ann Hematol
September 2025
Hematology Unit, Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy.
Daratumumab combined with bortezomib, thalidomide, and dexamethasone (Dara-VTD) is a highly effective induction therapy for newly diagnosed multiple myeloma (NDMM) patients eligible for autologous stem cell transplantation (ASCT). However, its impact on stem cell mobilization requires a critical evaluation. This study examines the effects of Dara-VTD on stem cell mobilization and collection outcomes.
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