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Lanostane triterpenoids from Ganoderma hainanense J. D. Zhao. | LitMetric

Lanostane triterpenoids from Ganoderma hainanense J. D. Zhao.

Phytochemistry

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China. Electronic address:

Published: June 2015


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Article Abstract

Chemical investigation of the fruiting bodies of Ganoderma hainanense resulted in isolation of fourteen lanostane triterpenoids, including nine ganoderma acids and five ganoderma alcohols, together with five known compounds. Structural elucidation was determined using extensive spectroscopic technologies, Mosher's method and X-ray single crystal diffraction. Three of the compounds showed inhibitory activities against HL-60, SMMC-7721, A-549 and MCF-7 cells with IC50 values of 15.0-40.0 μM.

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http://dx.doi.org/10.1016/j.phytochem.2014.10.009DOI Listing

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