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Objective: To investigate the effect of auricular stimulation in cavum conchae on the glycemic control for patients with type 2 diabetes mellitus.
Methods: Seventy-one cases were treated with auricular electrical stimulator in the cavum choncha for 30 min, once daily for consecutive 3 months. The changes on the fasting plasma glucose (FBG), 2-h postprandial blood glucose after a 75 g oral glucose load (P2BG), glycated hemoglobin (HbA1c), blood urea nitrogen (BUN), serum creatinine (SCr), total cholesterol (TC) and aspartate transaminase (AST) were compared before and after the treatment.
Results: The level of the HbA1c was significantly decreased (P<0.05), and there were also statistically significant decreases in BUN, SCr, TC and AST after the treatment (P<0.05). A few patients (n=7) reduced the dose of the hypoglycemic agents in response to repeated hypoglycemia during the treatment.
Conclusion: The stimulation in the cavum conchae of patients with types 2 diabetes mellitus may help decrease HbA1c, BUN, SCr, TC and AST, and may be an effective treatment for type 2 diabetes mellitus.
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http://dx.doi.org/10.1016/j.ctim.2014.09.002 | DOI Listing |
Cogn Affect Behav Neurosci
September 2025
Department of Behavioral and Cognitive Sciences, University of Luxembourg, Belval, 2, avenue de l'Universite, L- 4365, Esch sur-Alzette, Luxembourg.
Transcutaneous auricular vagus nerve stimulation (taVNS) affects autonomic function and enhances cognitive performance by increasing vagal activation and central noradrenergic activity. Nevertheless, the impact of taVNS on acute mental stress remains largely unexplored. This study examined whether taVNS can mitigate the acute sympathetic stress response and improve cognitive performance during a socially evaluated version of the Paced Auditory Serial Addition Task (PASAT).
View Article and Find Full Text PDFInt J Surg
September 2025
Division of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background: Functional dyspepsia (FD) is often comorbid with sleep disturbance. Transcutaneous auricular vagal nerve stimulation (taVNS) is a new and non-invasive therapeutic option. This study aimed to investigate its effects and possible mechanisms on FD with sleep disturbance.
View Article and Find Full Text PDFJAMA Netw Open
August 2025
Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Importance: Postpartum uterine contraction pain manifests as a severe, intermittent lower abdominal discomfort caused by uterine contraction during the early puerperium. Transcutaneous auricular vagus nerve stimulation (taVNS) has demonstrated promising effects in managing both acute and chronic pain conditions; however, there remains a paucity of studies regarding the use of taVNS for alleviating postpartum uterine contraction pain.
Objective: To investigate the effect of taVNS in alleviating postpartum uterine contraction pain among women receiving combined spinal-epidural anesthesia for elective cesarean delivery.
Healthcare (Basel)
August 2025
Department of Rehabilitation Sciences, Florida Gulf Coast University, Fort Myers, FL 33965, USA.
Cervicogenic headache (CGH) is a prevalent secondary headache disorder associated with upper cervical spine dysfunction, often involving nociceptive convergence at the trigeminocervical complex. While manual therapy and exercise have demonstrated benefit, autonomic dysregulation may contribute to persistent symptoms. This case report explores the integration of external vagus nerve stimulation (eVNS) into a multimodal physical therapy approach targeting both mechanical and neurophysiological contributors to CGH.
View Article and Find Full Text PDFJ Transl Gastroenterol
June 2025
Transtimulation Research Inc., Oklahoma, OK, USA.
Imbalanced autonomic function has been reported in gastrointestinal (GI) disorders. The vagus nerve is a major component in the regulation of upper GI motility. Vagal nerve stimulation (VNS) has been shown to improve symptoms of various GI disorders by enhancing parasympathetic activity.
View Article and Find Full Text PDF