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Most of ultrasound medical imaging systems currently on the market implement standard Delay and Sum (DAS) beamforming to form B-mode images. However, image resolution and contrast achievable with DAS are limited by the aperture size and by the operating frequency. For this reason, different beamformers have been presented in the literature that are mainly based on adaptive algorithms, which allow achieving higher performance at the cost of an increased computational complexity. In this paper, we propose the use of an alternative nonlinear beamforming algorithm for medical ultrasound imaging, which is called Delay Multiply and Sum (DMAS) and that was originally conceived for a RADAR microwave system for breast cancer detection. We modify the DMAS beamformer and test its performance on both simulated and experimentally collected linear-scan data, by comparing the Point Spread Functions, beampatterns, synthetic phantom and in vivo carotid artery images obtained with standard DAS and with the proposed algorithm. Results show that the DMAS beamformer outperforms DAS in both simulated and experimental trials and that the main improvement brought about by this new method is a significantly higher contrast resolution (i.e., narrower main lobe and lower side lobes), which turns out into an increased dynamic range and better quality of B-mode images.
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http://dx.doi.org/10.1109/TMI.2014.2371235 | DOI Listing |
Indian J Hematol Blood Transfus
July 2025
Department of Hematology and Bone Marrow Transplant, Paras Health, Gurugram, India.
There is scarcity of data on utility of inotuzumab ozogamicin (InO) in relapsed refractory acute lymphoblastic leukemia in India. This is a retrospective study. Twelve patients (3 children) with a median age of 22.
View Article and Find Full Text PDFNeurol Genet
August 2025
Epilepsy Neurogenetics Initiative, Division of Neurology, Children's Hospital of Philadelphia, PA.
Background And Objectives: Ring 20 syndrome is a rare childhood-onset neurodevelopmental disorder caused by a postzygotic event leading to a structural change in the 20th chromosome. Next-generation sequencing (NGS) does not identify an abnormality in the most common mosaic form. Through a systematic review of the literature, we sought to identify clinically distinct characteristics that would trigger an order for a karyotype, which is the only definitive diagnostic test for this condition.
View Article and Find Full Text PDFUltrasonics
December 2025
Biolab, PoliTo(BIO)Med Lab, Department of Electronics and Telecommunications, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Turin, Italy. Electronic address:
Beamforming, the process of reconstructing B-mode images from raw radiofrequency (RF) data, significantly influences ultrasound image quality. While advanced beamforming methods aim to enhance the traditional Delay and Sum (DAS) technique, they require access to raw RF data, which is often unavailable to researchers when using clinical ultrasound scanners. Given that Filtered Delay Multiply and Sum (F-DMAS) is known to provide superior image quality compared to conventional DAS, this study introduces the idea of employing generative adversarial networks (GANs) that transform plane wave DAS images into ones resembling those produced by F-DMAS.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
July 2025
Department of Ophthalmology, Boston Children's Hospital, Boston, Massachusetts, United States.
Purpose: Infantile nystagmus syndrome (INS) involves involuntary oscillatory eye movements, usually in the horizontal plane, beginning before six months of age. It is frequently associated with other eye diseases, including albinism. Pathological changes in the extraocular muscles (EOMs), including altered myofiber composition and decreased neuromuscular junction (NMJ) density, have been shown in albino mice and humans.
View Article and Find Full Text PDFUltrasonics
November 2025
Research Department of Surgical and Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, SE1 7EH, United Kingdom.
Coherent multi-transducer ultrasound (CoMTUS) imaging enables the use of multiple arrays as one large effective aperture yielding images with enlarged field-of-view, improved resolution, and higher signal-to-noise ratio. However, creating a large but discontinuous effective aperture increases the grating and sidelobe levels, and generates cross-talk artifacts between arrays. These additional challenges can degrade the contrast of the images obtained through the classic Delay and Sum (DAS) beamforming algorithm.
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