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We report the case of woman who presented a vulvar basal cell carcinoma (BCC) on the inner part of the labium majus, treated with local resection. Vulvar BCC is a rare cancer but can be long misdiagnosed due to a non-specific presentation. Though even rarer, BCC involving the mucosal side of the labium majus has to be considered in the differential diagnosis of the vulvar tumors. A complete excision with free margins is the treatment most recommended. Other recommendations include the early identification of aggressive subtypes, which carry a greater risk of recurrence and spreading potential as well as a long-term follow-up with exhaustive muco-cutaneous examination.
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http://dx.doi.org/10.4081/dr.2011.e37 | DOI Listing |
J Helminthol
September 2025
https://ror.org/039vw4178Institute for Sustainable Agriculture (IAS), Spanish National Research Council (CSIC), Department of Crop Protection, Avenida Menéndez Pidal s/n, 14004 Córdoba, Campus de Excelencia Internacional Agroalimentario, ceiA3, Spain.
The present study describes a new species, isolated from Meknès, Morocco, during nematode surveys conducted to investigate the biodiversity of plant-parasitic nematodes in Mediterranean olive groves and adjacent patches of natural vegetation. Application of integrative taxonomical approaches clearly verified that it is a new species designated herein as sp. nov.
View Article and Find Full Text PDFJ Invest Dermatol
August 2025
Department of Biological Chemistry, School of Medicine; Department of Dermatology, School of Medicine. Electronic address:
Vulvar diseases are a neglected area of women's health, profoundly affecting patients' quality of life. Lichen sclerosus (LS) is a chronic inflammatory vulvar skin disorder leading to severe itching, pain, scarring, and an increased risk of malignancy. Despite this burden, the molecular pathogenesis of vulvar LS (VLS) is not well understood, limiting treatment options.
View Article and Find Full Text PDFIndian Dermatol Online J
September 2025
Department of Dermatology and Venereology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Vulvar neoplasia is on the rise and patients often present to dermatologists with lesions of varying morphology associated with pruritus, burning sensation, or pain. Early diagnosis results in an early treatment and improved quality of life. Differentiating vulvar neoplasia and intraepithelial malignancies from benign and inflammatory conditions is imperative.
View Article and Find Full Text PDFJ Am Acad Dermatol
August 2025
Department of Dermatology, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Paris Cité, INSERM U 1342 , Paris, France.
Background: Anogenital basal cell carcinoma (BCC) is a rare and poorly understood subtype occurring in sun-protected areas.
Objective: To investigate the clinicopathological and genomic characteristics of anogenital BCC.
Methods: Patients with anogenital BCC diagnosed between 2006 and 2024 were included from a nationwide retrospective-prospective cohort.
Indian J Dermatol Venereol Leprol
July 2025
Department of Dermatology, Seoul National University College of Medicine, Jongno-Gu, Seoul, Korea.
Background Syringoma, a benign skin tumour characterised by stromal fibrosis and epithelial encirclement, suffers from limited treatment options. Aim This study aimed to analyse the correlation between mast cell density and histological features of syringomas, particularly stromal fibrosis and epidermal pigmentation. Methods Immunohistochemical staining with CD117 and estrogen receptor (ER)-α was performed in 49 samples from 47 patients of syringoma to assess mast cell density and ER-α expression.
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