Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349284 | PMC |
| http://dx.doi.org/10.3324/haematol.2014.111062 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Neutrophil cell surface receptor dynamics following trauma: a systematic review.
Eur J Trauma Emerg Surg
August 2025
Department of Traumatology, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Purpose: Neutrophils are essential effector cells in the immune response to traumatic injury. Although changes in receptor expression over time have been described in the literature, effective monitoring strategies are still lacking. This systematic review aims to identify reported neutrophil cell surface receptor dynamics after trauma and to determine the post-traumatic neutrophil signature over time, forming the basis for future immunomonitoring.
View Article and Find Full Text PDFCross-species protection suggests trogocytosis enables complement resistance through the transfer of negative regulators of complement activation.
Infect Immun
July 2025
Department of Microbiology and Molecular Genetics, University of California, Davis, California, USA.
is a major cause of diarrheal disease. trophozoites ("amoebae") can invade the intestine and disseminate via the bloodstream, resisting complement lysis through unknown mechanisms. Amoebae kill human cells by performing trogocytosis.
View Article and Find Full Text PDFRadiotherapy Upregulates the Expression of Membrane-Bound Negative Complement Regulator Proteins on Tumor Cells and Limits Complement-Mediated Tumor Cell Lysis.
Cancers (Basel)
July 2025
Molecular and Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, 69120 Heidelberg, Germany.
: Radiotherapy (RT) is a mainstay of clinical cancer therapy that causes broad immune responses. The complement system is a pivotal effector mechanism in the innate immune response, but the impact of RT is less well understood. This study investigates the interaction between RT and the complement system as a possible approach to improve immune responses in cancer treatment.
View Article and Find Full Text PDFA bioinformatic analysis to systematically unveil shared pathways and molecular mechanisms underlying monkeypox and its predominant neurological manifestations.
Front Cell Infect Microbiol
July 2025
Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: Monkeypox (MPOX) is a zoonotic disease caused by the MPOX virus (MPXV). MPOX resurfaced globally in May 2022, spreading throughout six WHO regions, resulting in nearly 87,000 cases and 112 deaths. Clinical symptoms include swollen lymph nodes, fever, joint pain and several neurological complications such as headache, encephalitis, myalgia, fatigue, photophobia and seizures.
View Article and Find Full Text PDFA Cluster of Acidic Residues in the Cytoplasmic Domain of SARS-CoV-2 Spike is Required for Virion-Incorporation and Infectivity.
bioRxiv
May 2025
VA San Diego Healthcare System, San Diego CA USA.
Like all coronaviruses, the infectivity of SARS-CoV-2 virus particles (virions) requires incorporation of the Spike glycoprotein. Yet, the mechanisms that support the virion-incorporation of Spike are incompletely defined. We noted an unusual feature of human sarbecovirus Spike proteins: their cytoplasmic domains (CDs) contain a stretch of acidic amino acids (DEDDSE).
View Article and Find Full Text PDF