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The authors examined whether changes in heart-rate (HR) variability (HRV) could consistently track adaptation to training and race performance during a 32-wk competitive season. An elite male long-course triathlete recorded resting HR (RHR) each morning, and vagal-related indices of HRV (natural logarithm of the square root of mean squared differences of successive R-R intervals [ln rMSSD] and the ratio of ln rMSSD to R-R interval length [ln rMSSD:RR]) were assessed. Daily training load was quantified using a power meter and wrist-top GPS device. Trends in HRV indices and training load were examined by calculating standardized differences (ES). The following trends in week-to-week changes were consistently observed: (1) When the triathlete was coping with a training block, RHR decreased (ES -0.38 [90% confidence limits -0.05;-0.72]) and ln rMSSD increased (+0.36 [0.71;0.00]). (2) When the triathlete was not coping, RHR increased (+0.65 [1.29;0.00]) and ln rMSSD decreased (-0.60 [0.00;-1.20]). (3) Optimal competition performance was associated with moderate decreases in ln rMSSD (-0.86 [-0.76;-0.95]) and ln rMSSD:RR (-0.90 [-0.60;-1.20]) in the week before competition. (4) Suboptimal competition performance was associated with small decreases in ln rMSSD (-0.25 [-0.76;-0.95]) and trivial changes in ln rMSSD:RR (-0.04 [0.50;-0.57]) in the week before competition. To conclude, in this triathlete, a decrease in RHR concurrent with increased ln rMSSD compared with the previous week consistently appears indicative of positive training adaptation during a training block. A simultaneous reduction in ln rMSSD and ln rMSSD:RR during the final week preceding competition appears consistently indicative of optimal performance.
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http://dx.doi.org/10.1123/ijspp.2014-0196 | DOI Listing |
Eur Urol Oncol
September 2025
Department of Urology, New York Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA. Electronic address:
Background And Objective: The apex-to-base transperineal (TP) prostate biopsy needle trajectory may better sample the anterior prostate than the transrectal approach. There is evidence that African American men are more likely to harbor anterior tumors, suggesting that TP biopsy would result in better detection in these men. We performed a secondary retrospective analysis of prospective randomized trial data to determine whether African American race is associated with anterior tumor location and better detection with TP biopsy.
View Article and Find Full Text PDFBr J Anaesth
September 2025
Department of Anaesthesia and Pain Management, Perth Children's Hospital, Perth, WA, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, WA, Australia; Institute for Paediatric Perioperative Excellence, The University of Western Austr
Background: Obstructive sleep apnoea (OSA) has been thought to increase the risk of respiratory depression from opioids. The primary aim of this study was to assess whether preoperative hypoxaemia by sleep study pulse oximetry imparts greater opioid sensitivity.
Methods: A multicentre observational cohort study with in-cohort dose randomisation was performed in children 2-8 yr of age with OSA undergoing adenotonsillectomy.
JACC Adv
September 2025
Section of Cardiovascular Medicine, Departments of Pediatrics and Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA. Electronic address:
Background: Adult congenital heart disease (ACHD) individuals have increased risk of noncardiac comorbidities including cancer and infections. Whether they are at increased risk of autoimmunity is unknown.
Objectives: The purpose of this study was to understand the association of ACHD and risk for autoimmunity.
Sports Med
September 2025
Harvard Medical School, Boston, USA.
Background: Physical training influences competitive marathon performance, including training volume and training frequency changes (TFCs) pre-race. Training intensity distribution (i.e.
View Article and Find Full Text PDFInt J Rheum Dis
September 2025
Department of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Objectives: Inclusion body myositis (IBM) can result in deadly respiratory consequences. Yet, the mechanism driving this issue remains equivocal. We mapped the literature to identify physiological respiratory characteristics in IBM and the types of respiratory assessments used.
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