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Objectives: To examine the effect of simulation-based seizure management teaching on improving caregiver competence and reported confidence with managing seizures. The authors hypothesized that simulation-based education would lead to a higher level of demonstrated competence and reported confidence in family members and caregivers. Simulation has not been previously studied in this context.
Methods: A two-group pre- and post-test experimental research design involving a total of 61 caregivers was used. The intervention was a simulation-based seizure curriculum delivered as a supplement to traditional seizure discharge teaching. Caregiver performance was analyzed using a seizure management checklist. Caregivers' perception of self-efficacy was captured using a self-efficacy questionnaire.
Results: Caregivers in the experimental group achieved significantly higher postintervention performance scores than caregivers in the control group in both premedication and postmedication seizure management (P<0.01). Additionally, they achieved significantly higher scores on the self-efficacy questionnaire including items reflecting confidence managing the seizure at home (P<0.05).
Conclusion: Caregivers receiving the supplemental simulation-based curriculum achieved significantly higher levels of competence and reported confidence, supporting a positive relationship between simulation-based seizure discharge education, and caregiver competence and confidence in managing seizures. Simulation sessions provided insight into caregiver knowledge but, more importantly, insight into the caregiver's ability to apply knowledge under stressful conditions, allowing tailoring of curriculum to meet individual needs. These findings may have applications and relevance for management of other acute or chronic medical conditions.
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http://dx.doi.org/10.1093/pch/19.7.373 | DOI Listing |
Epilepsy Res
September 2025
Medical Affairs, Torrent Pharmaceuticals Ltd, Ahmedabad 380009, India. Electronic address:
Objective: Primary generalized tonic-clonic seizures (pGTCS) are often misdiagnosed and remain challenging to manage due to limited treatment options. Lacosamide (LCM), approved for focal-onset seizures and adjunctive pGTCS therapy, was evaluated for real-world effectiveness in Indian patients.
Methods: This real-world, multicenter, retrospective, observational, and non-interventional study was conducted across 124 centers in India following approval from a centralized institutional ethics committee.
PLoS One
September 2025
Department of Neurology, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Background: The potential for racial disparity using urine drug screening (UDS) in patients with seizures is sparsely reported. This study aims to determine racial and ethnic disparities when ordering UDS in patients with suspected seizures in the emergency department (ED).
Methods: In this retrospective study, we identified patients over the age of 18 with suspected seizures who presented to the ED at the University of Kansas Medical Center between October 2017 and October 2020.
Epileptic Disord
September 2025
APHM, Timone Hospital, Epileptology and Cerebral Rhythmology, Marseille, France.
This case study reports the first documented use of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RFTC) to treat refractory status epilepticus (RSE). A 33-year-old woman with drug-resistant epilepsy and recurrent RSE underwent SEEG to define her epileptogenic zone. A new RSE started shortly before and continued during the SEEG exploration, being unresponsive to multiple antiseizure medications, vagal nerve stimulation, and corticosteroid therapy.
View Article and Find Full Text PDFCureus
August 2025
Psychiatry and Behavioral Sciences, West Virginia University, Morgantown, USA.
This study examined whether caregivers of male or female patients with epilepsy differ in perceived burden, social support, and coping mechanisms. In a cross-sectional design conducted at a tertiary neuropsychiatric hospital, 60 caregivers (30 per group) completed the Family Burden Interview Schedule (FBIS), the Social Support Questionnaire (SSQ), and the Ways of Coping Questionnaire (WCQ). Caregivers of female patients reported greater financial strain and more pronounced impacts on mental and physical health, yet they also perceived higher levels of social support.
View Article and Find Full Text PDFPatients with seizure disorders frequently present for anesthetic care, and anesthesiologists must be adequately equipped to manage these patients safely throughout the perioperative period. While Part I of this review focused on seizure diagnosis, classification, and treatment, Part II focuses on perioperative considerations for patients with seizure disorders. A detailed preoperative assessment is imperative as well as an in-depth understanding of the patient's medications and treatment modalities.
View Article and Find Full Text PDF