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Objective: To investigate the effectiveness of mirror therapy (MT) combined with bilateral arm training and graded activities to improve motor performance in the paretic upper limb after stroke.
Design: Randomized, controlled, assessor-blinded study.
Setting: Inpatient stroke rehabilitation center of a tertiary care teaching hospital.
Participants: Patients with first-time ischemic or hemorrhagic stroke (N=20), confined to the territory of the middle cerebral artery, occurring <6 months before the commencement of the study.
Intervention: The MT and control group participants underwent a patient-specific multidisciplinary rehabilitation program including conventional occupational therapy, physical therapy, and speech therapy for 5 d/wk, 6 h/d, over 3 weeks. The participants in the MT group received 1 hour of MT in addition to the conventional stroke rehabilitation.
Main Outcome Measures: The Upper Extremity Fugl-Meyer Assessment for motor recovery, Brunnstrom stages of motor recovery for the arm and hand, Box and Block Test for gross manual hand dexterity, and modified Ashworth scale to assess the spasticity.
Results: After 3 weeks of MT, mean change scores were significantly greater in the MT group than in the control group for the Fugl-Meyer Assessment (P=.008), Brunnstrom stages of motor recovery for the arm (P=.003) and hand (P=.003), and the Box and Block Test (P=.022). No significant difference was found between the groups for modified Ashworth scale (P=.647).
Conclusions: MT when combined with bilateral arm training and graded activities was effective in improving motor performance of the paretic upper limb after stroke compared with conventional therapy without MT.
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http://dx.doi.org/10.1016/j.apmr.2014.06.020 | DOI Listing |
Dev Med Child Neurol
September 2025
Queensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Aim: To compare active upper-limb therapies for children with cerebral palsy using a network meta-analysis.
Method: For this systematic review, five electronic databases were searched up to 2nd September 2024. Outcomes pertaining to improved hand use (Assisting Hand Assessment, AHA), goal attainment (Canadian Occupational Performance Measure, COPM), and self-care were analysed with therapies classified into 15 discrete categories.
BMJ Open
September 2025
Psychologial Neuroscience Laboratoy (PNL), Psychology Research Center (CIPSI), School of Psychology, University of Minho, Braga, Portugal
Introduction: Adolescence and youth are periods of significant maturational changes, which seem to involve greater susceptibility to disruptive events in the brain, such as binge drinking (BD). This pattern-characterised by repeated episodes of alcohol intoxication-is of particular concern, as it has been associated with significant alterations in the developing brain. Recent evidence indicates that alcohol may also induce changes in gut microbiota composition and that such disturbances can lead to impairments in both brain function and behaviour.
View Article and Find Full Text PDFPhantom pain (PP) is a neuropathic pain syndrome that occurs after limb amputation and is perceived in the absent body part. Its exact pathophysiology remains unclear but involves peripheral nerve lesions, central sensitization, and cortical reorganization. Psychological and social factors also play a significant role in its manifestation.
View Article and Find Full Text PDFSemin Oncol Nurs
August 2025
School of Nursing, Biobehavioral Health Sciences, University of Pennsylvania, Philadelphia.
Context: Caregivers are essential in the care of CAR T-cell patients, especially immediately before and after CAR T-cell therapy. However, the long-term CAR T-cell therapy caregiving implications are understudied.
Objectives: We aimed to characterize long-term caregiver health-related quality of life (HRQoL) and caregiving burden and understand the relationship between long-term caregiving burden and patient-reported HRQoL, cognitive function, and symptom burden.
J Rehabil Med
August 2025
Department of Physical Therapy for Pediatric, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Objective: This study aimed to compare the long-term effects of soft robotic gloves (SRGs) and mirror therapy on hand function and motor recovery in post-stroke patients.
Methods: A single-blinded, randomized controlled comparative study was conducted on 49 patients with chronic stroke assigned randomly to either the SRGs or mirror therapy group. Both groups underwent an 8-week intervention alongside conventional rehabilitation.