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http://dx.doi.org/10.1164/rccm.201402-0249LE | DOI Listing |
Chem Biodivers
September 2025
Department of Clinical Pharmacy, College of Pharmacy, University of Sulaimani, Sulaimani, Iraq.
The global rise in antibiotic resistance demands the urgent development of new antibacterial agents. This study investigated the antibacterial potential of four synthesized methoxy and thiophene chalcone derivatives (designated 3a, 4a, 3b, and 4b) against clinically relevant bacterial pathogens. These compounds were prepared through Claisen-Schmidt condensation, while their chemical structures were verified through applying Fourier-transform infrared, mass spectrometry, H nuclear magnetic resonance (NMR), and C NMR.
View Article and Find Full Text PDFInt J Surg Pathol
September 2025
Department of Pathology, The Thirteenth People's Hospital of Chongqing, Chongqing, China.
Soft tissue sarcomas are a heterogeneous group of malignancies arising from mesenchymal cells. Recent advancements in genomic profiling have identified novel gene fusions in these tumors, offering new insights into their pathogenesis and potential therapeutic targets. Here, we describe a spindle cell sarcoma harboring a novel gene fusion.
View Article and Find Full Text PDFJ Agric Food Chem
September 2025
College of Food Science and Engineering, Ocean University of China, Qingdao 266404, PR China.
Sulfated fucan has attracted growing attention due to its diverse biological properties. Endo-1,3-fucanases are valuable tools for the degradation of sulfated fucan. This study characterized an endo-1,3-fucanase Fun174Sb from the GH174 family, utilizing a combination of protein crystallography, mutagenesis, computational biology, and nuclear magnetic resonance techniques.
View Article and Find Full Text PDFBioelectromagnetics
September 2025
Competence Centre of Sleep Medicine, Charité -Universitaetsmedizin Berlin, Berlin, Germany.
A new whole-body exposure facility for a randomized, double-blind, cross-over provocation study investigating possible effects of 50 Hz magnetic field exposure on sleep and markers of Alzheimer's disease has been developed and dosimetrically analyzed. The exposure facility was custom-tailored for the sleep laboratory where the study was carried out and enables magnetic flux densities of up to 30 μT with a maximum field inhomogeneity of less than ± 20%. Exposure is applied fully software-controlled and in a blinded and randomized manner.
View Article and Find Full Text PDFAnal Chem
September 2025
Environmental NMR Center, University of Toronto, 1265 Military Trail, Toronto, Ontario M1C 1A4, Canada.
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique with a wide range of applications. To support the analysis of diverse and complex samples, various NMR tools and accessories have been created. Three-dimensional (3D) printing is an underutilized production method for NMR hardware, mainly due to the lack of H NMR background-free resins.
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