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Background: Ponseti serial casting is the most commonly used method in North America to treat children with clubfeet. Despite initial correction, recurrence is common. tibialis anterior tendon transfer (TATT) is commonly used to treat recurrent clubfeet. Recurrence can occur after TATT, and patients at risk of recurrence may benefit from closer monitoring. We studied the rate of second recurrence (recurrence after TATT) and studied the predictive factors for this recurrence.
Methods: Retrospective chart review of patients who have undergone TATT for recurrent clubfeet between 2002 and 2010 at our institution was performed. Recurrence was defined as recurrence of any elements of the clubfoot deformity that requires operative or nonoperative treatment. Effect of age at the time of TATT, initial severity of the deformity, and family history of clubfoot on rate of recurrence was studied.
Results: Sixty patients with 85 clubfeet were included in the study. Sixteen feet in 12 patients (20%) developed recurrence after TATT. Eight feet were treated nonoperatively and the rest (8 feet) required surgical procedure. Young age at time of TATT and brace noncompliance significantly increased the rate of second recurrence. Effect of severity of initial deformity and family history did not reach statistical significance.
Conclusions: Second recurrence can happen in around one fifth of patients with clubfeet after TATT. Patients with young age at TATT and patients with brace noncompliance are at an increased risk of recurrence and should be monitored closely.
Level Of Evidence: Level II-prognostic.
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http://dx.doi.org/10.1097/BPO.0000000000000248 | DOI Listing |
Ann Surg Oncol
September 2025
HepatoBiliaryPancreatic Surgery, AOU Careggi, Department of Experimental and Clinical Medicine (DMSC), University of Florence, Florence, Italy.
Purpose: To build computed tomography (CT)-based radiomics models, with independent external validation, to predict recurrence and disease-specific mortality in patients with colorectal liver metastases (CRLM) who underwent liver resection.
Methods: 113 patients were included in this retrospective study: the internal training cohort comprised 66 patients, while the external validation cohort comprised 47. All patients underwent a CT study before surgery.
Ann Surg Oncol
September 2025
Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Background: Postoperative late recurrence (POLAR) after 2 years from the date of surgical resection of hepatocellular carcinoma (HCC) represents a unique surveillance and management challenge. Despite identified risk factors, individualized prediction tools to guide personalized surveillance strategies for recurrence remain scarce. The current study sought to develop a predictive model for late recurrence among patients undergoing HCC resection.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Aim And Background: This study investigates the impact of D3 lymph node dissection extent on postoperative bowel function and nutritional status in patients undergoing radical surgery for right-sided colon cancer. Given that postoperative diarrhea can significantly affect the quality of life, we examined whether dissection boundaries influence these outcomes.
Methods: This was a prospective, randomized controlled trial conducted at a high-volume tertiary hospital.
Front Oncol
August 2025
Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Background: Low-grade endometrial stromal sarcoma (LG-ESS) is a rare malignant tumor of the female reproductive system with atypical clinical symptoms and slow progression.
Case: A 44-year-old female with a history of intermittent severe dysmenorrhea, previous laparoscopic myomectomy, and uterine artery embolization (UAE) presented with rapidly enlarging pelvic masses. Imaging revealed uterine masses suggestive of leiomyomas, although an adnexal origin could not be excluded.
Front Genet
August 2025
Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Background And Objective: Parental chromosomal structural variations (SVs) represent a primary genetic factor contributing to recurrent spontaneous abortion (RSA). Individuals carrying SVs with complex chromosomal rearrangements (CCRs) typically exhibit a normal phenotype but are at an increased risk of miscarriage. Current standard clinical detection methods are insufficient for the identification and interpretation of all SV types, particularly complex and occult SVs, thereby presenting a significant challenge for clinical genetic counseling.
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