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http://dx.doi.org/10.1016/j.clinph.2014.04.008 | DOI Listing |
J Med Internet Res
September 2025
School of Pharmacy, Sungkyunkwan University, Gyeonggi-do, Republic of Korea.
Background: Owing to the unique characteristics of digital health interventions (DHIs), a tailored approach to economic evaluation is needed-one that is distinct from that used for pharmacotherapy. However, the absence of clear guidelines in this area is a substantial gap in the evaluation framework.
Objective: This study aims to systematically review and compare the economic evaluation literature on DHIs and pharmacotherapy for the treatment of depression.
Interv Neuroradiol
September 2025
Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
IntroductionVenous sinus stenting (VSS) is an effective, less invasive alternative to ventriculoperitoneal shunting (VPS) for idiopathic intracranial hypertension (IIH). While efficacy is comparable, with some evidence favoring VSS for headache control, perioperative costs remain under-characterized due to reliance on reimbursement rates rather than actual expenditures.ObjectiveTo compare the perioperative cost of elective VSS and VPS for IIH, including outpatient workup and follow-up costs, using detailed institutional cost data.
View Article and Find Full Text PDFClin Orthop Relat Res
September 2025
Leni & Peter W. May Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Peripheral nerve injury commonly results in pain and long-term disability for patients. Recovery after in-continuity stretch or crush injury remains inherently unpredictable. However, surgical intervention yields the most favorable outcomes when performed shortly after injury.
View Article and Find Full Text PDFCereb Cortex
August 2025
Section on Functional Imaging Methods & Functional MRI Core Facility, National Institute of Mental Health, 10 Center Drive, Rm 1D80, Bethesda, MD 20892, United States.
Statistical Parametric Mapping (SPM) has been profoundly influential to neuroimaging as it has fostered rigorous, statistically grounded structure for model-based inferences that have led to mechanistic insights about the human brain over the past 30 years. The statistical constructs shared with the world through SPM have been instrumental for deriving meaning from neuroimaging data; however, they require simplifying assumptions which can provide results that, while statistically sound, may not accurately reflect the mechanisms of brain function. A platform that fosters the exploration of the rich and varying neuronal and physiologic underpinnings of the measured signals and their associations to behavior and physiologic measures needs a different set of tools.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Department of Biosciences, Integral University, Kursi Road, Lucknow, 226026, India.
Background: The river ecosystems provide habitats and source of water for a number of species including humans. The uncontrolled accumulation of pollutants in the aquatic environment enhances the development of antibiotic-resistant bacteria and genes.
Methods: Water samples were collected seasonally from different sites of Gomti and Ganga River.