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Primary colorectal lymphoma (PCL) is a rare condition that accounts for asmall percentage of all gastrointestinal (GI) malignancies. There are severalreports in the literature regarding the most common features of PCL. However,primary lymphoma in the rectosigmoid junction has been rarely reported. Ourcase was a 67-year-old male who presented with non-specific symptoms ofbowel obstruction which, upon further workup, was diagnosed as a rare case ofPCL located in the rectosigmoid junction.
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Viruses
July 2025
Faculty of Medicine, The Hashemite University, Zarqa 13133, Jordan.
Background: Cytomegalovirus (CMV) colitis is commonly seen in patients who are immunodeficient or have inflammatory bowel disease. Among the gastrointestinal sites affected by CMV, the colon is the most frequently affected, though rectal involvement is relatively rare. Reactivated CMV proctitis primarily occurs in elderly patients with comorbidities and is quite uncommon in immunocompetent individuals.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Department of Radiology, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen.
Introduction: Malignant peripheral nerve sheath tumors (MPNSTs) are rare and aggressive soft tissue sarcomas. Its occurrence in the gastrointestinal tract, particularly in the sigmoid colon, is exceptionally uncommon and poses significant diagnostic and therapeutic challenges.
Case Presentation: We report the case of a 46-year-old female who presented with a four-year history of intermittent rectal bleeding and lower abdominal pain.
Rom J Morphol Embryol
August 2025
Department of Surgery, University of Medicine and Pharmacy of Craiova, Romania;
Background∕Objectives: Malakoplakia is an uncommon clinicopathological entity defined by the accumulation of dysfunctional macrophages containing undigested bacterial remnants and pathognomonic Michaelis-Gutmann bodies. Although it most frequently involves the gastrointestinal tract, particularly the colon, rectum, and rectosigmoid junction, appendiceal involvement remains rare. This case represents only the fourth reported occurrence of appendiceal malakoplakia in a young, immunocompetent adult without notable comorbidities, underscoring its exceptional clinical presentation.
View Article and Find Full Text PDFFront Genet
August 2025
AMES, Centro Polidiagnostico Strumentale srl, Casalnuovo diNapoli, Italy.
Colorectal cancer (CRC) is a leading cause of cancer-related death, with metastases typically involving the liver, lungs, and peritoneum. Choroidal metastases are extremely rare. We report a case of metastatic CRC with choroidal involvement, characterized by longitudinal genomic profiling using the TruSight Oncology 500 assay.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
July 2025
Internal Medicine Gastroenterology Department, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Background And Studys Purpose: Endoscopic band ligation is commonly used in gastroenterology but limited in colorectal polyps (CRPs) treatment due to narrow cap diameters. Endoscopic mucosal resection and endoscopic submucosal dissection (ESD) are effective but carry higher bleeding risks in patients with concomitant comorbidities. Considering the narrowest part of the colon, the rectosigmoid junction measures approximately 2.
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