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Minimally invasive plate osteosynthesis (MIPO) has been used for humeral shaft fractures, but concerns exist about soft tissue injuries. The purpose of this study was to report the surgical technique and clinical outcomes of MIPO using a helical plate for metadiaphyseal complex humeral shaft fractures. Twelve patients with acute displacement involving proximal and middle third humeral shaft fractures (AO type C) were treated using the MIPO technique with a helical plate. Fracture union, complications, and functional outcomes were evaluated using the Constant-Murley score and Mayo Elbow Performance Score (MEPS) at final follow-up. All fractures united at an average of 17.9 weeks. No major complications, such as neurovascular injury, infection, and nonunion, were observed. Mean Constant-Murley and MEPS scores at final follow-up were 88.6 and 97.9, respectively. A MIPO technique using a helical plate can be a useful surgical option for metadiaphyseal complex fractures of the humeral shaft.
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http://dx.doi.org/10.3928/01477447-20140225-55 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Endocrine Unit, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, United States.
The parathyroid hormone receptor type 1 (PTH1R) is a G protein-coupled receptor that mediates the actions of parathyroid hormone (PTH) in the regulation of blood calcium levels, as well as PTH-related protein (PTHrP) in the regulation of skeletal development. Severe loss-of-function homozygous mutations in PTH1R are incompatible with life as in Blomstrand's lethal chondrodysplasia, characterized by accelerated growth plate ossification. More recently, homozygous mutations located in the transmembrane helices, extracellular domains and C-tail of the PTH1R were identified in patients with milder conditions characterized by variable degrees of skeletal and mineral abnormalities.
View Article and Find Full Text PDFIndian J Orthop
August 2025
The Fracture & Orthopaedic Clinic, K.S. Orthopaedic Foundation, 57, 17-A Cross, 8 th Main Rd., Malleswaram, Bangalore, 560055 India.
Background: Humerus shaft osteoporotic fractures are common in the elderly due to higher fall risk and osteoporotic bone, 80% of these fractures in >60 years age group occur in women. Low energy fractures have high union rates and reasonable function with nonoperative treatment. Less commonly, the osteoporotic patient may sustain polytrauma, high energy injury or open injury to the arm.
View Article and Find Full Text PDFRelativistic vortex laser generation has recently emerged as a focal point in the field of laser-plasma interaction. However, most studies have primarily focused on generating vortex lasers with topological charge || ≤ 3, leaving a significant gap in the generation of high-order modes (|| ≥ 4) relativistic vortex lasers with high mode purity. In this study, we propose a novel scheme employing axial line-focused pinhole plates (ALPP) to generate ultra-intense high-order-mode vortex lasers with high mode purity.
View Article and Find Full Text PDFJ Opt Soc Am A Opt Image Sci Vis
June 2025
Due to the existence of orbital angular momentum, an optical vortex generated from spiral zone plates is an important approach for studying physics and detecting matter. However, the unneeded high-order diffraction inherent in traditional spiral zone plates will add background noise, leading to complication in subsequent analysis. In this paper, a single-focus spiral zone plate with an approximately sinusoidal transmittance, called phase quasi-random squares spiral zone plates (PQRSZPs), is designed.
View Article and Find Full Text PDFA perfect vortex beam (PVB) is a wavefront helically structured beam that has the capacity to transport Orbital Angular Momentum (OAM). PVB is typically generated by Bessel Gaussian beams, which can be modulated by phase modulation devices, such as spiral phase plates and SLMs. However, these methods are constrained by the redundancy of the operational devices and the singular order of the beams.
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