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Nonadherence to recommended pneumococcal conjugate vaccine (PCV) schedules may have implications for protection against pneumococcal disease. In this commentary, we have assessed adherence to the recommended dosing schedules (the completion of the primary PCV and booster series) in different European countries. We found that adherence with the PCV schedule was lower than that for diphtheria-tetanus-acellular pertussis (DTaP) and that higher adherence was observed in countries where PCV vaccination is recommended and funded. Adherence with the booster dose is often lower than that with the primary series completion, and it is often given after the recommended age. These data highlight the need to encourage timely vaccination of children with PCV, in line with local immunization schedules. There is no single solution to improve adherence; actions need to be tailored to the context of individual countries through initiatives at the national, regional, and local levels and should target different stakeholders.
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http://dx.doi.org/10.1016/j.clinthera.2014.03.001 | DOI Listing |
Biomacromolecules
September 2025
Department of Chemistry, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea.
Marine biofouling poses significant economic and environmental challenges, highlighting the need for effective antifouling coatings. We report amphiphilic poly(SBMA--EGDEA) copolymer coatings that resist both marine diatom adhesion and sediment adsorption. The coatings were synthesized via surface-initiated ATRP and RAFT polymerization using hydrophilic sulfobetaine methacrylate (SBMA) and hydrophobic ethylene glycol dicyclopentenyl ether acrylate (EGDEA).
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Department of Psychiatry, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
Background: Internet-based cognitive behavioral therapies (iCBTs) are typically categorized into 2 types: therapist-assisted and self-guided. Both formats have accumulated substantial evidence supporting their cost-effectiveness and efficacy in treating a range of mental health conditions. However, therapist-assisted iCBTs tend to show lower dropout rates than self-guided versions.
View Article and Find Full Text PDFAm J Public Health
October 2025
Alexander Furuya, Asa Radix, Adam Whalen, Jessica Contreras, Jenesis Merriman, Krish J. Bhatt, Roberta Scheinmann, and Dustin T. Duncan are with the Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY. Yusuf Ransome is with the Department of Social and Behav
To examine how one's community connectedness may act as a source of resilience and promote HIV prevention and care behaviors among transgender women of color. We analyzed survey data from 313 transgender women of color living in New York City collected from August 2020 to November 2022. The Community Connectedness Scale asks participants about their baseline feelings of connection, feelings of inclusion, feelings of belonging, feelings of isolation, and feelings of being unlike in relation to the transgender community.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
August 2025
Department of Gastroenterology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi People's Hospital, Wuxi, Jiangsu Province, China.
Background: Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, significantly impact patients' lives. Effective management often involves invasive and costly monitoring.
Objective: To evaluate the feasibility of integrating home-based fecal calprotectin testing with therapeutic drug monitoring (TDM) in managing moderate-to-severe IBD.
JMIR Hum Factors
September 2025
Villa Beretta Rehabilitation Center, Costa Masnaga, Italy.
Background: Telerehabilitation is a promising solution to provide continuity of care. Most existing telerehabilitation platforms focus on rehabilitating upper limbs, balance, and cognitive training, but exercises improving cardiovascular fitness are often neglected.
Objective: The objective of this study is to evaluate the acceptability and feasibility of a telerehabilitation intervention combining cognitive and aerobic exercises.