Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Requests for comprehensive searches, such as searches to support systematic reviews, seem to be evolving into routine practice in the health sciences library environment. Collecting terminology for these searches is often a time-consuming process. This case study reports on the development of a searchable Web-based repository, MedTerm Search Assist, as a means for librarians to share biomedical terminology from systematic review searches.

Download full-text PDF

Source
http://dx.doi.org/10.1080/02763869.2014.897518DOI Listing

Publication Analysis

Top Keywords

web-based repository
8
biomedical terminology
8
terminology systematic
8
systematic review
8
review searches
8
case study
8
searches
5
development web-based
4
repository sharing
4
sharing biomedical
4

Similar Publications

FungiSNC: An integrated database for fungi small non-coding RNAs based on high-throughput sequencing.

J Adv Res

August 2025

Microbiology and intelligent biomanufacturing Key Laboratory of Sichuan Province, College of Life Science, Sichuan University, Chengdu, Sichuan 610041, China. Electronic address:

Introduction: Small non-coding RNAs (sncRNAs) have been proven to play crucial roles in various biological processes such as development, stress responses, virulence, and pathogenicity. However, to the best of our knowledge, none of the currently available databases can store, manage, and analyze the vast amounts of sncRNA sequencing data. A comprehensive web-based platform for the integration and analysis of sncRNAs in fungi and their potential functions is still lacking.

View Article and Find Full Text PDF

Background: The FDA approval of T cell receptor-engineered T cells (TCR-T) for synovial sarcoma demonstrates the potential for adoptive T cell therapies (ACTs) in solid tumors. However, the paucity of tumor-associated targets without expression in normal tissues remains a major bottleneck, especially in rare cancer subtypes.

Methods: We developed a comprehensive computational pipeline called SCAN-ACT that leverages single-cell RNA sequencing and multi-omics data from tumor and normal tissues to nominate and prioritize putative targets for both chimeric antigen receptor (CAR)- and TCR-T cells.

View Article and Find Full Text PDF

A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers.

J Vis Exp

July 2025

Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne; Australian Regenerative Medicine Institute, Monash University; Stem Cell Medicine Department, Murdoch Children's Research Institute, The Royal Children's Hospital; The Novo Nordisk Foundation Cent

Enhancers are DNA regions that regulate gene expression. Mutations within enhancers can result in abnormal gene regulation leading to disease. Therefore, identifying enhancers that regulate gene activity in specific tissues is crucial for understanding the genetic basis of disease.

View Article and Find Full Text PDF

Here we present a new iPSC resource of apparently healthy subject biospecimens available to the research community through the National Institute of General Medical Sciences Human Genetic Cell Repository (NIGMS Repository). This resource includes five iPSCs and matched parental cell lines with accompanying publicly available, HiFi whole-genome sequencing data. Structural variant (SV) and single nucleotide variant (SNV) concordance between iPSC and parental lines was generally high; however, we found a notable reduction in concordance between the iPSC reprogrammed with retroviral reprogramming and its parental line consistent with previous work showing newer Sendai approaches to be more robust in preserving genomic integrity.

View Article and Find Full Text PDF

Background: Chronic kidney disease (CKD) is a progressive and devastating condition affecting over 10% of the global population, with more than 800 million individuals impacted worldwide. Anemia, a critical and debilitating complication of CKD, accelerates disease progression and exacerbates its overall burden. Despite numerous studies exploring the prevalence and determinants of anemia in CKD in Ethiopia, the pooled prevalence remains undefined, highlighting a critical gap in evidence.

View Article and Find Full Text PDF