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Objectives: Korean regression models for spirometric reference values are different from those of other ethnic groups. The purpose of this study was to evaluate discordance in spirometric interpretations based on using Korean reference equations versus non-Korean reference equations.
Methods: Spirometry was performed on 825 Korean male workers from April 2009 to November 2011. The spirometric patterns and disease severity were evaluated using two Korean equations (Choi's and Lee's) and three equations for Caucasians (NHANES III, Morris's, and Knudson's), and the results of Choi's equation were compared with the non-Korean equations. The spirometric patterns were defined as normal, restrictive, and mild and moderate obstructive.
Results: The mean differences in the FEV1% and FVC% between the two Korean equations were 2.0 ± 1.3% and 3.5 ± 2.2%, respectively. Morris's equation had the greatest difference in the FEV1% from Choi's equation: 32.9 ± 8.5%. Knudson's equation had the greatest difference in the FVC% from Choi's equation: 10.5 ± 6.5%.
Conclusions: The two Korean equations shared similar characteristics of spirometric interpretation. The spirometric interpretations of Choi's equation were significantly different from those of Morris's equation and Knudson's equation.
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http://dx.doi.org/10.1186/2052-4374-25-42 | DOI Listing |
PLoS Comput Biol
September 2025
Department of Mathematical Sciences, KAIST, Daejeon, Republic of Korea.
Mathematical modeling is a powerful tool for understanding and predicting complex dynamical systems, ranging from gene regulatory networks to population-level dynamics. However, model predictions are highly sensitive to initial conditions, which are often unknown. In infectious disease models, for instance, the initial number of exposed individuals (E) at the time the model simulation starts is frequently unknown.
View Article and Find Full Text PDFSci Rep
August 2025
School of Electrical Engineering, Korea University, Seoul, 02841, South Korea.
Lithium-titanate oxide (LTO) batteries are widely adopted in transportation owing to their high safety, long lifespan, and excellent high C-rate capability. However, studies investigating the thermal runaway behavior of LTO cells under railway operating conditions are limited. In particular, the influence of fault scenarios and environmental factors on battery safety and passenger evacuation time warrants further investigation.
View Article and Find Full Text PDFJ Neurosci Methods
August 2025
Signal and Image Processing Institute, Ming Hsieh Department of Electrical and Computer Engineering, University of Southern California, Los Angeles, CA, 90089, USA.
Background: Automated estimation of cortical thickness in brain MRI is a critical step when investigating neuroanatomical population differences and changes associated with normal development and aging, as well as in neurodegenerative diseases such as Alzheimer's and Parkinson's. The limited spatial resolution of the scanner leads to partial volume effects, where each voxel in the scanned image may represent a mixture of more than one type of tissue. Due to the highly convoluted structure of the cortex, this can have a significant impact on the accuracy of thickness estimates, particularly if a hard intensity threshold is used to delineate cortical boundaries.
View Article and Find Full Text PDFEur Radiol
August 2025
Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Objective: We evaluated the value of EC as a major feature for hepatocellular carcinoma (HCC) and its implications on simplifying LI-RADS v2018: by either excluding EC (LI-RADS[EC(-)]), or treating EC as equivalent to other major features (LI-RADS[EC(+)]).
Materials And Methods: This retrospective study included patients who underwent preoperative MRI within 1 month of surgery. Two radiologists independently assigned LI-RADS categories, with consensus resolution.
Disabil Rehabil
August 2025
Department of Physical Therapy, Woosong University, Daejeon, Republic of Korea.
Purpose: This study aimed to develop a U.S.-specific reference equation for the 6-Minute Walk Test (6MWT) in individuals with Class III obesity and compare its performance with the Italian model by Capodaglio et al.
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