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http://dx.doi.org/10.1016/j.jaci.2013.10.045 | DOI Listing |
Anal Chim Acta
November 2025
HIV-1 Molecular Epidemiology Laboratory, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Microbiology Department, Hospital Universitario Ramón y Cajal, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, 28034, Spain. Electronic address:
Background: Currently, 39.9 million people are infected with the human immunodeficiency virus (HIV), and 1.3 million new infections occur annually, with over 170 circulating variants.
View Article and Find Full Text PDFAnn Rheum Dis
September 2025
Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany; Hannover Medical School, Cluster of Excellence RESIST (EXC 2155), Hannover, Germany. Electronic address:
Objectives: IκBα controls the canonical activation of NFκB. IκBα gain-of-function due to NFKBIA variants affecting the N-terminus of IκBα-especially residues 32 and 36-manifests with combined immunodeficiency. The role of NFKBIA variants affecting other IκBα domains has not been described.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
Fundació Lluita contra les Infeccions, Badalona, Spain.
Background: The intestinal microbiota composition has been linked to neurocognitive impairment in people with HIV (PWH). However, the potential interplay of microbial species and related metabolites, particularly in the context of an HIV cure strategy remains underexplored. The BCN02 trial evaluated the impact of romidepsin (RMD), used as a HIV-1 latency reversing agent and with reported beneficial neurological effects, combined with the MVA.
View Article and Find Full Text PDFCureus
August 2025
Obstetrics and Gynecology, Mount Sinai Hospital, Chicago, USA.
Cervical cancer is rarely reported in patients with congenital adrenal hyperplasia (CAH), a condition that may alter risk through hormonal and anatomical factors. When combined with human immunodeficiency virus (HIV), the risk of progression from cervical intraepithelial neoplasia (CIN) to invasive carcinoma may be amplified, yet remains underreported. We report the case of a 57-year-old woman with a history of classic CAH, HIV, cervical intraepithelial neoplasia grade III (CIN III), hypertension, and asthma who presented with abdominal pain and pneumaturia.
View Article and Find Full Text PDFOncol Lett
November 2025
Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China.
Lung adenocarcinoma (LUAD) remains one of the most prevalent and lethal cancers globally, making it critical to understand the mechanisms driving its progression and improve prognosis. Moreover, cuproptosis and mitochondrial dysfunction may be involved in lung cancer. Therefore, the present study aimed to identify mitochondrial genes associated with cuproptosis to develop a prognostic model for patients with LUAD, with the potential to predict survival outcomes and responses to treatment.
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