Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
It is crucial to understand the distribution of embolic agents inside target liver during and after the hepatic portal vein embolization (PVE) procedure. For a long time, the problem has not been well solved due to the radiolucency of embolic agents and the resolution limitation of conventional radiography. In this study, we first reported use of fluorescent carboxyl microspheres (FCM) as radiolucent embolic agents for embolizing hepatic portal veins. The fluorescent characteristic of FCM could help to determine their approximate location easily. Additionally, the microspheres were found to be fairly good embolizing agents for PVE. After the livers were excised and fixed, they were imaged by in-line phase contrast imaging (PCI), which greatly improved the detection of the radiolucent embolic agents as compared to absorption contrast imaging (ACI). The preliminary study has for the first time shown that PCI has great potential in the pre-clinical investigation of PVE with radiolucent embolic agents.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851775 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080919 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Additional In Vivo Study of Arterial Embolization with a Novel Agar-Based Embolic Agent: Feasibility and Efficacy of New-Size Implants for Improved Microcatheter Injectability.
Cardiovasc Intervent Radiol
September 2025
LIIE, Aix Marseille University, Marseille, France.
Computational fluid dynamics (CFD) modelling of liquid embolic agents (Onyx) used in brain arteriovenous malformation (AVM) treatment to predict the distal penetration behavior.
Med Eng Phys
October 2025
Ansys Inc., Houston, TX 77094, USA.
Introduction: Benchtop and animal models have traditionally been used to study the propagation of Onyx Liquid Embolic Systems (Onyx) used in the treatment of brain arteriovenous malformations (AVM). However, such models are costly, do not provide sufficient detail to elucidate how variations in Onyx viscosity alter flow dynamics, and rely on some trial-and-error, resulting in elongated timelines for product development.
Objectives: The goal of this study was to leverage Computational Fluid Dynamics (CFD) simulations to predict the behavior of different Onyx formulations.
Transvenous curative embolization of brain arteriovenous malformations using extra-low viscosity Obtura versions: Initial experience and technical insights.
Interv Neuroradiol
September 2025
J.J. Merland Department of Therapeutic Neuroangiography, University General Hospital of Catalonia and Hospital del Mar, Barcelona, Spain.
Background and purposeThis study presents our initial experience using Obtura, a novel nonadhesive liquid embolic agent with extra-low viscosity variants, in transvenous curative embolization of brain arteriovenous malformations (bAVMs). We assess the agent's performance and compare its advantages with other extra-low viscosity options currently available.Materials and methodsFive patients (three females, two males; mean age, 33 years; range, 20-55 years) with ruptured bAVMs were treated using the transvenous retrograde pressure cooker technique (TVRPCT).
View Article and Find Full Text PDFComputational Fluid Dynamics of the Flow of the Deformable Toroidal Embolic Agents Within Straight and Stenotic Pipes by Full Eulerian FSI Method.
Int J Numer Method Biomed Eng
September 2025
Department of Chemical System Engineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
The effect of shape and size of embolic agents on embolization phenomena has been discussed clinically for transcatheter arterial chemoembolization (TACE). We numerically discussed the unique embolization behavior of new deformable toroidal microparticles in blood vessels by computational fluid dynamics simulations. We employed an Eulerian-Eulerian (full Eulerian) fluid-structure interaction (FSI) method to analyze the flow and deformation behaviors of a deformable torus in a cylindrical pipe.
View Article and Find Full Text PDFTranscatheter Arterial Embolization with N-butyl-2-cyanoacrylate-Lipiodol for Downsizing of the Autosomal Dominant Polycystic Kidneys: A Case Report with Long-term Evaluation.
Interv Radiol (Higashimatsuyama)
June 2025
Department of Radiology, Oita University Faculty of Medicine, Japan.
This case report describes a 56-year-old woman with autosomal dominant polycystic kidney disease and chronic renal failure who underwent transcatheter arterial embolization with N-butyl-2-cyanoacrylate-Lipiodol before renal transplantation. Both kidneys were significantly enlarged, necessitating transcatheter arterial embolization to reduce renal volume and create space for transplantation. The right kidney volume decreased from 2520 to 1150 mL within 9 months after transcatheter arterial embolization, enabling successful transplantation.
View Article and Find Full Text PDF