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A 65-year-old woman with bullous pemphigoid presented with fever and several red-purple nodular subcutaneous lesions on both lower legs 1 week after starting treatment with azathioprine (AZA). Biopsy of a skin nodule was compatible with erythema nodosum (EN) and hypersensitivity reaction to AZA was suspected. AZA was subsequently discontinued, observing complete remission of fever and EN within 2 weeks. This case highlights the importance of recognizing EN as a possible manifestation of hypersensitivity reaction to AZA.
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http://dx.doi.org/10.4103/0019-5154.117332 | DOI Listing |
Turk J Pediatr
September 2025
Division of Allergy and Asthma, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
Animal allergens, particularly those from cats, dogs, and horses, are significant risk factors for the development of allergic diseases in childhood. Managing animal allergies requires allergen avoidance and, when this is not feasible, specific immunotherapy. Patient history remains the cornerstone of diagnosis, providing the foundation for diagnostic algorithms.
View Article and Find Full Text PDFAppl Neuropsychol Child
September 2025
Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Sensory processing (SP) difficulties, such as heightened sensitivity to sensory input, have been linked to prolonged recovery and persistent post-concussive symptoms in adults following mild traumatic brain injury (mTBI). However, research on SP across different sensory inputs after pediatric mTBI is limited. This study examined SP patterns in children and adolescents aged 6-17 years with mTBI at 2 weeks and 6 months post-injury.
View Article and Find Full Text PDFPediatr Pulmonol
September 2025
Department of Pediatrics, Division of Pulmonology, Indiana University of School of Medicine, Indianapolis, Indiana, USA.
Introduction: Prior studies of pediatric asthma control and lung function after COVID-19 have been limited by short follow-up intervals. We aimed to evaluate symptom control and lung function in children with asthma up to 34 months post-COVID-19.
Methods: We conducted a prospective observational chart review study.
Top Magn Reson Imaging
October 2025
BIOSPACE LAB, Nesles-la-Vallée, France.
Aims: Cardiac tumors are aggressive and asymptomatic in early stages, causing late diagnosis and locoregional metastasis. Currently, the standard of care uses gadolinium-based contrast agents for MRI, and the associated hypersensitivity reactions are a significant concern, such as gadolinium deposition disease. In addition, the proximity of cardiac lesions closer to vital structures complicates surgical interventions.
View Article and Find Full Text PDFTurkiye Parazitol Derg
September 2025
Karadeniz Technical University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Trabzon, Türkiye.
Leukocytoclastic vasculitis (LCV) is a type of vasculitis that affects small vessels and is commonly associated with infections, malignancies, drugs, and autoimmune diseases. In this case, a 75-year-old female patient presented with clinical signs of LCV, and after ruling out common etiologies, hydatid disease (HD) emerged as a potential cause. This case highlights the importance of considering parasitic infections, particularly HD, in the differential diagnosis of LCV, especially in regions where these infections are endemic and in patients exposed to relevant environmental risk factors.
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