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Total knee arthroplasty (TKA) is a cost-effective procedure used to treat degenerative knee disease with excellent long-term outcomes. However, TKA has not always resulted in excellent functional and patient satisfaction outcomes, partly due to the use of prostheses that did not reproduce natural knee kinematics. Due to a paucity of reports on single-radius designs, the authors evaluated the clinical and patient-reported outcomes of primary TKA in patients who had received a single-radius prosthesis. A total of 287 TKAs from 7 centers were prospectively evaluated. Mean follow-up was 5 years, with each patient undergoing year re-evaluation. Kaplan-Meier implant survivorship was 99.7% at a final follow-up of 7 years. The total reoperation rate was 1.4%. Clinical outcomes demonstrated significant improvements in Knee Society, Short Form 36, and activity scores at a mean follow-up of 5 years. The authors believe that various features of this prosthesis may have contributed to these excellent outcomes. Further longer-term studies are necessary to better evaluate these outcomes.
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http://dx.doi.org/10.3928/01477447-20130624-17 | DOI Listing |
J Assist Reprod Genet
September 2025
Department of Gynecology, Pingxiang Maternal and Child Health Hospital, PingXiang, Jiangxi, China.
Objective: This study aimed to identify key predictors of uterine fibroid (UF) recurrence following laparoscopic myomectomy (LM) in reproductive-age women and to construct a predictive nomogram to support individualized clinical decision-making.
Methods: This retrospective cohort study included 459 women who underwent LM. Recurrence of UFs and risk of recurrence were analyzed.
Clin Rheumatol
September 2025
Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN, 55906, USA.
Objectives: IgG4-related disease (IgG4-RD) can affect multiple organ systems, with coronary artery involvement being rare. Coronary periarteritis may lead to complications such as myocardial infarction and ischemic cardiomyopathy. This case series characterizes the clinical and radiological features, complications, and treatment strategies in patients with IgG4-RD-associated coronary periarteritis.
View Article and Find Full Text PDFEur J Pediatr
September 2025
Paediatric Pain and Palliative Care Service, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Purpose: This study aimed to describe the structure, patient characteristics, and preliminary clinical outcomes of a dedicated interdisciplinary outpatient clinic for paediatric chronic and complex pain in Italy, with a focus on the feasibility of implementing a biopsychosocial care model.
Methods: We conducted a retrospective review of all patients referred to the Paediatric Specialised Pain Clinic of the University of Padua between January 2023 and May 2024. Data on demographics, clinical diagnoses, pain characteristics, treatments, and follow-up outcomes were collected.
Aesthetic Plast Surg
September 2025
Department of Plastic Surgery, The First Affiliated Hospital, Jinan University, No. 613 West, Huangpu Avenue, Guangzhou, 510630, Guangdong Province, China.
Background: Microfocused ultrasound (MFU) is a non-invasive technique used for facial rejuvenation, yet there is limited quantitative data on its long-term effects. This study aimed to evaluate the long-term efficacy and safety of MFU for facial rejuvenation. We utilized standardized photography along with advanced skin assessment technologies to analyze the impact of MFU on facial morphology, skin function, and patient satisfaction over a 12-month period.
View Article and Find Full Text PDFNat Rev Urol
September 2025
Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Low-grade non-muscle invasive bladder cancer is a specific category of bladder cancer with a favourable prognosis; however, its management presents several challenges. The risk of stage progression is very low, but approximately half of patients will experience recurrence within the first 5 years after diagnosis. This high propensity for recurrence, coupled with the threat of progression, mandates ongoing surveillance.
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