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http://dx.doi.org/10.1183/09031936.00170912 | DOI Listing |
Equine Vet J
September 2025
Department of Clinical Sciences, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec, Canada.
Background: Steaming hay reduces respirable particles and is commonly used to feed horses with asthma. However, it showed inconsistent benefits in clinical studies.
Objectives: (1) To assess the effects of steamed hay on lung function and airway inflammation in horses with severe equine asthma (SEA) in remission; (2) To compare these effects with a dry hay diet.
Ann Allergy Asthma Immunol
September 2025
Department of Pneumology, University Hospital Saint-Luc, Brussels, Belgium; Pole Pneumology, ENT, and Dermatology - LUNS, Institute of Experimental and Clinical Research (IREC), UCLouvain, Brussels, Belgium.
Background: Different biologics available as add-on treatment for severe asthma (SA) showed modest benefits on lung function parameters but head-to-head comparisons are lacking.
Objective: This study aims to compare the effects of four biologics on lung function parameters (including small airways) at 6 and 12 months of treatment in patients with SA.
Methods: An observational multicenter study was conducted on adults patients with SA naïve to biologics treated by benralizumab, dupilumab, mepolizumab and omalizumab with lung function assessment by spirometry and gas dilution method at baseline (T0), after 6 (T6) and 12 months (T12) of treatment.
Cell Signal
September 2025
Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Respiratory Immunology research center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer mortality. 2.48 million new cases were reported globally in 2022, driven by rising adenocarcinoma rates linked to environmental factors such as air pollution.
View Article and Find Full Text PDFJ Endocrinol
September 2025
School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor Darul Ehsan, Malaysia.
Gut dysbiosis and an increased risk of respiratory infection in type 2 diabetes have been well recognised. However, the relationship between the gut and respiratory pathobionts carriage rate in the Type 2 diabetic Malaysian population is understudied. To address the knowledge gap, we profiled the gut and upper respiratory tract microbial composition, as well as the urine metabolome of 31 type 2 diabetic adults and 14 non-diabetes adults.
View Article and Find Full Text PDFFront Physiol
August 2025
School of Mechanical Engineering and IEDT, Kyungpook National University, Daegu, Republic of Korea.
Introduction: Quantitative computed tomography (qCT) provides detailed spatial assessments of lung structure and function, while electrical impedance tomography (EIT) offers high temporal resolution for analyzing breathing patterns but lacks structural detail. This study investigates the correlation between qCT-based spatial variables and EIT-based temporal signals to elucidate the physiological relationships between these two modalities.
Methods: Six participants with asthma underwent pulmonary function tests (PFTs) before and after bronchodilator inhalation.