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Purpose: The purposes of this study were to establish reference values for renal size determined from 99mTc-MAG3 renal scintigraphy and to derive regression equations to predict normal limits.
Methods: The study population consisted of 106 subjects evaluated for kidney donation who underwent 99mTc-MAG3 renal scintigraphy. Renal length, width, and area were determined from the pixel length and area of whole-kidney regions of interest and correlated with patient sex, height, weight, body mass index, and body surface area (BSA). Reference values were obtained based on estimation of the lower and upper percentiles via quantile regression.
Results: The mean (SD) left and right kidney lengths was 12.2 (1.0) and 12.1 (1.0) in male and 11.9 (0.9) and 11.8 (0.9) in female patients, respectively. Sex was not a significant factor in the quantile regression models. Regression equations defining the lower and upper limits of renal length (cm) and area (cm) are as follows: left kidney length (5th percentile), 8.2+1.3×BSA; left kidney length (95th percentile), 9.1+2.3×BSA; right kidney length (5th percentile), 8.8+1.0×BSA; right kidney length (95th percentile), 11.1+1.4×BSA; left kidney area (5th percentile), 32.5+9.6×BSA; left kidney area (95th percentile), 12.6+31.7×BSA; right kidney area (5th percentile), 16.1+18.5×BSA; right kidney area (95th percentile), 32.6+22.2×BSA.
Conclusions: Regression equations have been developed, which define the upper and lower limits of renal size from 99mTc-MAG3 images and may assist in the detection of unsuspected bilateral increases or decreases in renal size.
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http://dx.doi.org/10.1097/RLU.0b013e318270866f | DOI Listing |
Gynecol Endocrinol
December 2025
National Clinical Research Center for Obstetric & Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Objective: To expand the clinical phenotype associated with MYRF mutations in disorders of sex development (DSDs).
Methods: We present a case of a 17-year-old patient with a female phenotype who presented with primary amenorrhea.
Results: The patient's external genitalia was entirely female in appearance, though there was no opening of vagina below the orifice of urethra.
Surg Radiol Anat
September 2025
Department of Anatomy, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Purpose: This study aimed to report and characterize bilateral renal artery (RA) variations observed during cadaveric dissection and to evaluate these findings in the context of embryological development and morphometric analysis.
Case Presentation: During routine anatomical dissection of an 87-year-old Caucasian male cadaver, bilateral variations in the renal arteries were identified. On the right side, two renal arteries (RRA1 and RRA2) were observed, each giving rise to presegmental and segmental branches.
Ann Thorac Surg
September 2025
Department of Cardiac Surgery, University of Michigan, Ann Arbor, MI. Electronic address:
Background: The need for renal replacement therapy (RRT) is an uncommon but severe complication following post-cardiac surgery AKI, however there is limited data on the incidence of renal recovery. This study evaluates the rate of renal recovery in cardiac surgery patients that require postoperative RRT and survive to discharge, and describes the clinical factors associated with higher rates of recovery.
Methods: All adult patients without preoperative dialysis, heart transplantation, or durable left ventricular assist device who required new onset postoperative RRT after cardiac surgery from 2011-2022 at a high-volume referral center were included.
Case Rep Pediatr
September 2025
Department of Pediatrics, Nemours Children's Hospital Florida, Orlando, Florida, USA.
We describe the clinical presentation and evaluation of an 11-year-old girl with no reported past medical history, seen by her primary care physician for intermittent knee pain. Outpatient X-rays revealed findings concerning for rickets, prompting further evaluation with blood work. The patient was urgently referred to the emergency department due to abnormal laboratory results and was subsequently found to be in end-stage kidney disease with severe anemia, metabolic acidosis, and significant electrolyte abnormalities.
View Article and Find Full Text PDFClin Kidney J
September 2025
Hypertension is a pervasive and progressive complication in chronic kidney disease (CKD) patients, affecting up to 90% of those in advanced stages or on dialysis. A particularly insidious aspect of this condition is nocturnal hypertension, characterized by high blood pressure (BP) during sleep and a blunted or absent nighttime BP dipping-phenomena associated with accelerated CKD progression and increased cardiovascular risk. Despite its strong prognostic significance, nocturnal hypertension remains underdiagnosed due to limited use of ambulatory BP monitoring.
View Article and Find Full Text PDF