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Pindborg tumor, the eponymous counterpart of calcifying epithelial odontogenic tumor (CEOT), is a rare benign odontogenic neoplasm that was first described by a Dutch pathologist Jens Jorgen Pindborg in 1955 and accounts for approximately 1% of all odontogenic tumors. Its origin as well as its malignant potential is controversial. This neoplasm is possibly of stratum intermedium origin and occurring predominantly in the mandible of adults. We hereby report a case of Pindborg tumor arising in the premaxilla which is seldom (9 out of 200 cases) documented in the scientific literature.
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Head Neck Pathol
July 2025
Division of Pathology, Department of Diagnostic & Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan.
J Clin Exp Dent
May 2025
School of Dentistry, Dentistry Post-Graduate Program, Oral and Maxillofacial Surgery Residency Program at University Hospital of Cam pos Gerais (HUCG), State University of Ponta Grossa (UEPG), Ponta Grossa, Brazil.
This case report presents a rare instance of a Calcifying Epithelial Odontogenic Tumor (CEOT) in the maxilla of a 52-year-old male, characterized by a painless, growing mass and facial asymmetry. Imaging revealed extensive involvement of the maxillary sinus, nasal cavity, pterygoid plate, and infraorbital margin. Histopathological analysis confirmed the diagnosis, showing polyhedral odontogenic epithelium with amyloid-like material.
View Article and Find Full Text PDFHead Neck Pathol
March 2025
Surgical Pathology Laboratory, Oral Pathology Department, Facultad de Odontología, Universidad de Buenos Aires, M.T. Alvear 2142. (C1122AAH), Ciudad Autónoma de, Buenos Aires, Argentina.
Aim: The aim of the present work was to analyze 20 cases of calcifying epithelial odontogenic tumour (CEOT), also known as "Pindborg tumour", and contrast the data with findings reported in the literature.
Materials And Methods: Twenty cases of CEOT filed in the archives of the Surgical Pathology Laboratory of the Oral Pathology Department, School of Dentistry, University of Buenos Aires, over a period of 63 years (1960-2023) were retrieved. Their histopathological, histochemical-immunohistochemical, and clinical-radiographic features were evaluated, and the obtained data were compared with those reported in the literature.
J Pharm Bioallied Sci
December 2024
Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath University (BIHER), Chennai, Tamil Nadu, India.
Calcifying epithelial odontogenic tumor (CEOT), first identified by Jens Jorgen Pindborg in 1955, is a rare developmental odontogenic tumor, accounting for approximately 0.4% of all such tumors and most commonly occurring in the third and fourth decades of life. A 63-year-old man presented with a painful swelling in the right lower face, which had progressively enlarged over four months.
View Article and Find Full Text PDFRom J Morphol Embryol
February 2025
Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania; Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; madilazar@elear
Pindborg tumor is a calcifying epithelial odontogenic tumor possibly arising from developmental disturbances in dental lamina remnants. It predominantly affects individuals in their third decade of life, with women also experiencing later onset. The tumor exists in two forms, namely intraosseous (central) and extraosseous (peripheral), with the former showing higher post-surgery recurrence rates of about 14%.
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