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Article Abstract
We report the use of the platelet glycoprotein IIb/IIIa antagonist tirofiban for cardiac surgery in a small child with active heparin-induced thrombocytopenia type II, including description of the postoperative course.
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Brexpiprazole in the Management of Schizophrenia: A Consensus Report of Best Practices From Acute to Maintenance Treatment.
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Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, New York, USA.
Brexpiprazole is a second-generation antipsychotic with multiple indications, including the treatment of schizophrenia. As a partial dopamine agonist, brexpiprazole differs from most other antipsychotics, yet uncertainties about its full mechanism of action have led to some ambiguity among prescribers. To address this gap, an international panel of psychiatric experts was organized and convened with funding from Otsuka Pharmaceutical Europe Ltd and H.
View Article and Find Full Text PDFA comparative study of EEG functional and effective connectivity patterns in children with learning difficulties during reading and math tasks.
Front Neurosci
August 2025
School of Psychology, Hainan Normal University, Haikou, China.
Introduction: This study utilized electroencephalography (EEG) to compare brain functional and effective connectivity patterns in children with reading difficulties (RD) and math difficulties (MD) during specific tasks. The aim was to identify neurophysiological distinctions between these two learning disorders, which often exhibit high comorbidity.
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Parapharyngeal Space Ganglioneuroma in a Child: A Report of a Rare Case.
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Pathology, Hanoi Medical University, Hanoi, VNM.
Parapharyngeal space (PPS) tumors are extremely rare in the pediatric population, accounting for a small fraction of all head and neck neoplasms. The majority of neoplasms in the PPS are benign tumors. We present a case of an eight-year-old male with a large PPS ganglioneuroma, who presented with a neck mass that had been progressing over five years with no symptoms of dysphasia.
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View Article and Find Full Text PDFAlternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived mesenchymal stem cells.
Front Bioeng Biotechnol
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Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, United States.
Background: Mesenchymal stem cells (MSCs) hold great promise for treating a variety of human diseases; however, their clinical translation is hindered by challenges in large-scale expansion while preserving therapeutic potency and maintaining small cell size. Conventional 2D culture on rigid substrates induces MSC senescence and enlargement, compromising their function and biodistribution.
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