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Carotid-cavernous fistulas (CCFs) are traumatic or spontaneously occurring communications between the carotid artery and the cavernous sinus. Carotid-cavernous fistulas can be due to a direct connection or indirect connections between the carotid artery system and the cavernous sinus. According to the etiologic classification, they may be of traumatic or spontaneous origin, and according to the angiography classification, they may be of direct or dural. Most CCFs are of spontaneous origin, and these are reported as frequently self-healing lesions. Spontaneous CCFs are mostly secondary to arteriosclerotic changes, which explains the increased ratio of elderly patients. Traumatic CCFs are usually of high-flow type and need intervention. The symptoms are various usually correlated to the size and type of venous drainage. The most frequent symptoms on presentation are proptosis, conjunctivitis, and chemosis; however, this picture may be complicated by optic nerve edema, cranial nerve palsies, and intracranial hemorrhage. We report a case with right low-flow dural CCF, which has worsened after angiography and recovered totally soon after endovascular embolization process.
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http://dx.doi.org/10.1097/SCS.0b013e31822ea840 | DOI Listing |
Front Med (Lausanne)
July 2025
Department of Ophthalmology, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou Red-Cross Hospital, Hangzhou, China.
Carotid cavernous fistula (CCF) is a pathological condition where an abnormal connection forms between the carotid artery and the cavernous sinus. This condition can lead to a variety of ocular and neurological symptoms, often making it difficult to diagnose, especially when patients present with common ocular complaints such as red eye, which is often misdiagnosed as conjunctivitis. The subtle and diverse symptoms of CCF can lead to misdiagnosis, delaying appropriate treatment.
View Article and Find Full Text PDFJ Neuroendovasc Ther
August 2025
Department of Neurosurgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Objective: This case report describes the successful coil embolization of a direct carotid-cavernous fistula (d-CCF) caused by aneurysmal rupture in an older patient with residual aortic dissection, via direct puncture of the common carotid artery (CCA).
Case Presentation: A 95-year-old woman presented with progressive right periorbital swelling, pain, and eye redness. Cranial imaging revealed proptosis, dilated superior and inferior ophthalmic veins, and a ruptured aneurysm of the right internal carotid artery (ICA), leading to a diagnosis of d-CCF.
J Neurosurg Case Lessons
August 2025
Department of Neurosurgery, Osaka Red Cross Hospital, Osaka, Osaka, Japan.
Background: Thirteen cases of fungal cavernous-carotid aneurysms (CCAs) attributable to invasive fungal sinusitis have been reported in the literature. These reports included only 1 case of carotid-cavernous fistula (CCF). In this report, the authors present a case of CCF attributable to the rupture of an infected CCA caused by invasive fungal sinusitis that required proximal occlusion for treatment.
View Article and Find Full Text PDFBMJ Case Rep
July 2025
Radiology, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia.
Paradoxical worsening phenomenon is a rare event following the treatment of carotid cavernous sinus fistula (CCF). In the present case, a late adolescent male presenting with left eye redness and proptosis was found to have an indirect left CCF. Two days after successful embolisation of the fistula, the patient developed clinical deterioration of the left eye.
View Article and Find Full Text PDFRadiol Case Rep
September 2025
Radiology Department of the Specialty Hospital, Hassan II University Hospital, Fez, Morocco.
Carotid-cavernous fistula (CCF) is an abnormal communication between the main trunk of carotid artery or its branches and the cavernous sinus. Most of the cases of CCF occur following head trauma, but congenital and spontaneous cases have been reported. We report the case of a 47-year-old patient, who initially consulted (in 2012) for headache, tinnitus and diplopia on the left side, without history of trauma, for 1 month before his consultation.
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