Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Esophageal giant fibrovascular polyps are rare and are thought to represent redundant tumorlike or hamartomatous esophageal folds. Although most patients present with slowly evolving dysphagia, a minority present with acute respiratory distress or even death caused by asphyxia. We present the pathologic and cytogenetic findings of an 18-cm esophageal giant fibrovascular polyp in a 49-year-old woman who presented with odynophagia and dysphagia. The histologic findings are that of classic esophageal giant fibrovascular polyp as previously described in the literature. Cytogenetic study revealed an abnormal karyotype, and comparative genomic hybridization analysis showed regional amplifications of chromosomes 3 and 12 and a possible loss of 22q13.3-qter. The significance of these cytogenetic findings is unclear but may suggest a neoplastic process in the pathogenesis of esophageal giant fibrovascular polyps.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.humpath.2011.04.022 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phenotyping and Clinical Utility of Phagocytic Polyploid Giant Cancer Macrophages in Blood.
Cancer Lett
September 2025
Fox Chase Cancer Center, Protocol Support Laboratory, 333 Cottman Ave., Philadelphia, PA 19111, USA.
Historically, polyploid giant cancer cells (PGCCs) within tumors have been ignored as superfluous inflammatory refuse with no intrinsic clinical or biological relevance. However recently, multiple studies have described the existence PGCCs in solid tumor masses that appear to correlate with tumor progression, and can also appear in blood circulation as cancer associated macrophage like cells (CAMLs). In an effort to understand the clinical and biological role of CAMLs (i.
View Article and Find Full Text PDFPredictors for Achieving Textbook Outcomes After Endoscopic Resection of Giant Submucosal Tumors in the Esophagus and Cardia.
Dig Dis Sci
September 2025
Zhongshan Hospital, Endoscopy Center and Endoscopy Research Institute, Fudan University, Shanghai, China.
Background And Aims: Endoscopic resection for submucosal tumors (SMTs) in the esophagus and cardia is challenging with hazards of adverse events and the exploration of its achieving textbook outcome (TO) was unknown. We aim to investigate the predictors of TO for giant SMTs with a long diameter ≥ 7 cm or a transverse diameter ≥ 3.5 cm.
View Article and Find Full Text PDFA Rare Case of Giant Esophageal Leiomyoma in an Adult Male Presenting With Right Upper Quadrant Pain and Mild Dysphagia.
Cureus
August 2025
Medicine and Pediatrics, University of California Los Angeles David Geffen School of Medicine, Los Angeles, USA.
Leiomyomas are the most common benign mesenchymal tumors of the esophagus, and they account for nearly two-thirds of benign esophageal neoplasms. The leiomyomas of the esophagus present with numerous nonspecific symptoms and signs, including dysphagia, shortness of breath, anorexia, weight loss, chronic cough, and bowel obstruction. The patient in this case report presented with moderate to severe right upper quadrant pain and mild dysphagia, which initially prompted evaluation for hepatobiliary pathology.
View Article and Find Full Text PDFBreaking Boundaries: A Case Report of Giant Hiatal Hernia Housing Pancreas, Stomach, Small Bowel, and Colon.
Cureus
August 2025
Gastroenterology, Boonshoft School of Medicine, Wright State University, Dayton, USA.
Hiatal hernia (HH) is defined as the protrusion of abdominal contents through the esophageal hiatus of the diaphragm into the mediastinum. They are classified into categories I-IV. Type I, known as the sliding hernia, accounts for up to 90% of HH cases and are typically managed medically.
View Article and Find Full Text PDFCase Report: The huge esophageal displacement: a case of dramatic esophageal interfraction motion during neoadjuvant chemotherapy and immunotherapy.
Front Immunol
August 2025
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Background: The average movement of esophagus is about 0.15 to 0.4 cm radially and 0.
View Article and Find Full Text PDF