Clues for c-Yes involvement in the cell cycle and cytokinesis.

Cell Cycle

Department of Cell Biology and Anatomy, Southern Alberta Cancer Research and Hotchkiss Brain Institutes, University of Calgary; Calgary, Alberta, Canada.

Published: May 2011


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http://dx.doi.org/10.4161/cc.10.9.15495DOI Listing

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Clues for c-Yes involvement in the cell cycle and cytokinesis.

Cell Cycle

May 2011

Department of Cell Biology and Anatomy, Southern Alberta Cancer Research and Hotchkiss Brain Institutes, University of Calgary; Calgary, Alberta, Canada.

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We have previously reported that c-Src is activated by mercuric chloride (HgCl(2)). We investigated the mechanism of this activation and found that in vitro activation of c-Src by HgCl(2) did not require tyrosine residues at 416 and 527. Both SH2 and SH3 domains of c-Src were dispensable for the activation by HgCl(2).

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