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A simple dielectric hollow-tube has been experimentally demonstrated at terahertz range for bio-molecular layer sensing based on the anti-resonant reflecting wave-guidance mechanism. We experimentally study the dependence of thin-film detection sensitivity on the optical geometrical parameters of tubes, different thicknesses and tube wall refractive indices, and on different resonant frequencies. A polypropylene hollow-tube with optimized sensitivity of 0.003 mm/μm is used to sense a subwavelength-thick (λ/225) carboxypolymethylene molecular overlayer on the tube's inner surface, and the minimum detectable quantity of molecules could be down to 1.22 picomole/mm(2). A double-layered Fabry-Pérot model is proposed for calculating the overlayer thicknesses, which agrees well with the experimental results.
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http://dx.doi.org/10.1364/OE.18.019353 | DOI Listing |
JMIR Hum Factors
September 2025
KK Women's and Children's Hospital, Singapore, Singapore.
Background: Breast cancer treatment, particularly during the perioperative period, is often accompanied by significant psychological distress, including anxiety and uncertainty. Mobile health (mHealth) interventions have emerged as promising tools to provide timely psychosocial support through convenient, flexible, and personalized platforms. While research has explored the use of mHealth in breast cancer prevention, care management, and survivorship, few studies have examined patients' experiences with mobile interventions during the perioperative phase of breast cancer treatment.
View Article and Find Full Text PDFACS Sens
September 2025
METU MEMS Center, Ankara 06530, Türkiye.
Cardiovascular diseases (CVDs) remain a leading cause of death, particularly in developing countries, where their incidence continues to rise. Traditional CVD diagnostic methods are often time-consuming and inconvenient, necessitating more efficient alternatives. Rapid and accurate measurement of cardiac biomarkers released into body fluids is critical for early detection, timely intervention, and improved patient outcomes.
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September 2025
Department of Electrical and Computer Engineering, Inha University, Incheon 22212, Republic of Korea.
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia with multiple clinical manifestations and complications, such as cardiovascular disease, kidney dysfunction, retinal impairment, and peripheral neuropathy. Continuous and minimally invasive glucose monitoring is essential for effective DM management. Microneedles (MNs)-based sensing platforms offer a promising solution; however, conventional polymeric MNs suffer from limited electrochemical sensitivity due to their insufficient electroactive surface area and inefficient loading of catalytic and enzymatic components.
View Article and Find Full Text PDFSmall
September 2025
Institute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Kaiserstraße 12, 76131, Karlsruhe, Germany.
Recently, metal-organic frameworks (MOFs) have shown high potential in the field of sensing. However, fluorescent-based detection with MOFs in solution needs complex pre-treatments and has stability issues, complicating measurements and handling for sensing applications. Here, an easy-to-handle and low-cost strategy is introduced to convert MOF-based sensing from solution to surface using scanning probe lithography.
View Article and Find Full Text PDFAnal Methods
September 2025
Key Laboratory of Biorheological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, P. R. China.
Aflatoxin B1 (AFB1) is one of the most toxic mycotoxins that pose great health threats to humans. Herein, an aptasensor-based fluorescent signal amplification strategy is developed for the detection of AFB1. Initially, the AFB1 aptamers labelled with carboxyfluorescein (FAM) are adsorbed onto graphene oxide (GO), triggering energy transfer.
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