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Objective: To investigate significance of the distribution and thickness of cancellous and cortical bone in the mandibular ramus using computed tomography (CT) in the design of osteotomy at the medial aspect of the ramus.
Methods: 45 cases with class III prognathism underwent CT before operation. The distribution and thickness of cancellous and cortical bone in the mandibular ramus was measured every 2.5 mm thick from mandibular lingular plane to 20 mm above it.
Results: The upper ramus was separated by cancellous bone in only 37.5% of the cases. The other cases had no cancellous bone in the upper ramus. 5 mm above the lingual, the thickness of cortical bone at the lingual aspect decreased from the front to the behind with an average thickness of 1.55 mm. The distance from lingual to the fusion at the posterior border of ramus was 9.45 mm.
Conclusions: The medial cortical osteotomy should be located within 5 mm above the lingual and within 9.45 mm posterior to the lingular. The osteotomy could be slightly oblique and become deeper from behind to the front with an average depth of about 2 mm.
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J Biomech Eng
September 2025
Texas Tech University Box 41021 Lubbock, TX 79409.
Wrist biomechanics remain incompletely understood due to the complexity of experimental measurements in this multi-bone joint system. Finite element analysis provides a powerful alternative for investigating internal variables such as carpal kinematics and displacement patterns. This technical brief compares two bone representation approaches, all-cortical versus cortical-trabecular, using two distinct finite element models developed from the same wrist CT dataset.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Medical Imaging, Central Laboratory of Jinan Stomatological Hospital, Jinan Key Laboratory of Oral Tissue Regeneration, Jinan, Shandong Province, China.
Abstract Rationale: Nonossifying fibroma (NOF) is one of the benign bone tumors in adolescents, and it rarely occurs in the jawbone. According to the site of onset, it is divided into the cortical type and the medullary type. Currently, there is no case report of medullary NOF in the mandible of the elderly.
View Article and Find Full Text PDFBone Rep
September 2025
Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 1215 21st Ave. S., Suite 4200, Nashville, TN 37232, USA.
This study applied Raman spectroscopy (RS) to ex vivo human cadaveric femoral mid-diaphysis cortical bone specimens ( = 118 donors; age range 21-101 years) to predict fracture toughness properties via machine learning (ML) models. Spectral features, together with demographic variables (age, sex) and structural parameters (cortical porosity, volumetric bone mineral density), were fed into support vector regression (SVR), extreme tree regression (ETR), extreme gradient boosting (XGB), and ensemble models to predict fracture-toughness metrics such as crack-initiation toughness (K) and energy-to-fracture (J-integral). Feature selection was based on Raman-derived mineral and organic matrix parameters, such as νPhosphate (PO)/CH-wag, νPO/Amide I, and others, to capture the complex composition of bone.
View Article and Find Full Text PDFIndian J Endocrinol Metab
August 2025
Department of Endocrinology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Introduction: Benign adrenal tumours are frequently seen in endocrinology, affecting mostly men in middle aged. But incidentalomas are more common in the elderly. Functional adrenal tumours most commonly secrete cortisol, aldosterone and very rarely, oestrogen.
View Article and Find Full Text PDFBone
September 2025
Department of Mechanical Engineering, Texas A&M University, 3123 TAMU, College Station, TX, 77843, United States of America; School of Engineering Medicine, Texas A&M University, 1020 Holcombe Blvd, Houston, TX 77030, United States of America. Electronic address:
Breast, prostate and lung cancer cells frequently metastasize to bone, leading to disruption of the bone microstructure. This study utilized mechanical testing with micro-CT imaging, digital volume correlation (DVC), and atomic force microscopy (AFM) nanomechanical testing to examine the mechanical property variations in mouse long bones (tibia) with metastatic lung cancer cell involvement, spanning from the whole-bone scale to the microstructural level. In addition, we also investigated how metastatic invasion alters the morphology of hydroxyapatite nanocrystals in bone at the nanometer scale.
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