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RiceGeneThresher is a public online resource for mining genes underlying genome regions of interest or quantitative trait loci (QTL) in rice genome. It is a compendium of rice genomic resources consisting of genetic markers, genome annotation, expressed sequence tags (ESTs), protein domains, gene ontology, plant stress-responsive genes, metabolic pathways and prediction of protein-protein interactions. RiceGeneThresher system integrates these diverse data sources and provides powerful web-based applications, and flexible tools for delivering customized set of biological data on rice. Its system supports whole-genome gene mining for QTL by querying using DNA marker intervals or genomic loci. RiceGeneThresher provides biologically supported evidences that are essential for targeting groups or networks of genes involved in controlling traits underlying QTL. Users can use it to discover and to assign the most promising candidate genes in preparation for the further gene function validation analysis. The web-based application is freely available at http://rice.kps.ku.ac.th.
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http://dx.doi.org/10.1093/nar/gkn638 | DOI Listing |
JMIR Med Inform
September 2025
Global Health Economics Centre, Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Background: Artificial intelligence (AI) algorithms offer an effective solution to alleviate the burden of diabetic retinopathy (DR) screening in public health settings. However, there are challenges in translating diagnostic performance and its application when deployed in real-world conditions.
Objective: This study aimed to assess the technical feasibility of integration and diagnostic performance of validated DR screening (DRS) AI algorithms in real-world outpatient public health settings.
JMIR Hum Factors
September 2025
Media Psychology Lab, Department of Communication Science, KU Leuven, Leuven, Belgium.
Background: Out-of-hospital cardiac arrests (OHCAs) are a leading cause of death worldwide, yet first responder apps can significantly improve outcomes by mobilizing citizens to perform cardiopulmonary resuscitation before professional help arrives. Despite their importance, limited research has examined the psychological and behavioral factors that influence individuals' willingness to adopt these apps.
Objective: Given that first responder app use involves elements of both technology adoption and preventive health behavior, it is essential to examine this behavior from multiple theoretical perspectives.
J Med Internet Res
September 2025
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The loss of a loved one is a common yet stressful event in later life. Internet- and mobile-based interventions have been proposed as an effective treatment approach for individuals with prolonged grief.
Objective: The AgE-health study aimed to investigate the efficacy of an eHealth intervention, trauer@ktiv, in reducing prolonged grief symptoms in a sample of older adults.
Int J Comput Assist Radiol Surg
September 2025
Institute of Computer Science, Friedrich-Schiller-Universität, Fürstengraben 1, 07743, Jena, Thuringia, Germany.
Purpose: Cerebral aneurysms are blood-filled bulges that form at weak points in blood vessel walls, and their rupture can lead to life-threatening consequences. Given the high risk associated with these aneurysms, thorough examination and analysis are essential for determining appropriate treatment. While existing tools such as ANEULYSIS and its web-based counterpart WEBANEULYSIS provide interactive means for analyzing simulated aneurysm data, they lack support for collaborative analysis, which is crucial for enhancing interpretation and improving treatment decisions in medical team meetings.
View Article and Find Full Text PDFComplement Ther Med
September 2025
Fukuoka City Hospital, Fukuoka 812-0046, Japan.
Objectives: Dyslipidemia is a significant risk factor for cardiovascular disease. Traditional treatments often focus on pharmacological interventions; however, alternative therapies, such as hot spring and sauna use, have recently gained attention because of their potentially beneficial effects on lipid profiles and cardiovascular health.
Design And Setting: This systematic review aimed to synthesize current evidence on the efficacy of hot spring and sauna use, alone or combined with exercise therapy, in improving blood lipid profiles, with a focus on mechanisms, benefits, and limitations.