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Contact dermatitis to isocyanates is a problem and is usually described within industrial settings. A patient who developed an acute allergic contact dermatitis using a dicyclohexylmethane-4,4'-diisocyanate (DMDI)-charged cartridge to create resin-coated '3D labels' within an office environment is described.
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http://dx.doi.org/10.1111/j.1600-0536.2007.01290.x | DOI Listing |
J Tissue Viability
September 2025
Swedish Centre for Skin and Wound Research (SCENTR), School of Health Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Faculty of Medicine a
Background: Incontinence-associated dermatitis (IAD) is a prevalent and distressing form of irritant contact dermatitis caused by prolonged exposure to urine and/or faeces. Not all incontinent individuals develop IAD, suggesting that additional prognostic factors contribute to its onset. The quality of empirical evidence supporting risk factors for IAD development is moderate to very low.
View Article and Find Full Text PDFJ Drugs Dermatol
September 2025
Background: Sunscreens can reduce skin cancer and sunburn. Recent studies on dermal penetration have raised concerns about the safety of sunscreens with organic ultraviolet (UV) filters.
Objective: The aim of the retrospective study was to assess the dermal safety of chemical sunscreens containing the chemical filters avobenzone, octocrylene, homosalate, and octisalate.
Front Immunol
September 2025
Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland.
This review presents the current knowledge on the potential of mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) in the treatment of various skin diseases such as psoriasis, atopic dermatitis, contact dermatitis, systemic sclerosis, graft-versus-host disease, alopecia areata, and systemic lupus erythematosus. MSCs can modulate the immune response and release growth factors and cytokines that promote tissue regeneration and healing and reduce inflammation. In turn, EVs' ability to transport various biological molecules, including microRNAs (miRNAs), makes them potential therapeutic agents.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
August 2025
Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Irritant contact dermatitis (ICD) is a common inflammatory skin condition caused by direct cytotoxic effects of irritants on the epidermis. Topical corticosteroids, while effective for treating inflammatory dermatoses, may paradoxically induce adverse skin reactions when misused. This case highlights ICD triggered by self-administration of compound clobetasol propionate ointment, exacerbated by undiagnosed type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDFZhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
August 2025
Outpatient Department of Changzhou Center for Disease Control and Prevention, Changzhou 213022, China.
Sinomenine hydrochloride is an alkaloid preparation commonly used in clinical practice in traditional Chinese medicine, and allergic reactions induced by occupational exposure to it are relatively rare in clinical settings. This article analyzes a case of allergic contact dermatitis in a medical worker after occupational exposure to sinomenine hydrochloride. The patient developed generalized skin rashes with the fingertips as the initial site three months after exposure to sinomenine hydrochloride.
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