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The aim of the present study was to investigate the variability in permanent tooth emergence sequences in Flemish children. Data were obtained in the Signal-Tandmobiel project, a 6-yr prospective longitudinal oral health screening survey in Belgium. Bayesian statistical analyses, taking into account the interval-censored character of the data, were performed. The analyses indicated that no sequence was common in a quadrant to more than 19% of the sample. When only those emergence sequences are considered with a prevalence of 1% or more, 21 variations can be expected in the maxilla and 15-22 variations in the mandible. These variations 'cover' 84-88% of all sequences. The presentation of emergence sequences solely based on means or medians should thus be regarded as misleading.
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http://dx.doi.org/10.1111/j.1600-0722.2007.00505.x | DOI Listing |
Microb Genom
September 2025
International Centre of Excellence for Aquatic Animal Health, The Centre for Environment, Fisheries and Aquaculture Science, Weymouth, DT4 8UB, UK.
High rates of mortality of the common cockle, , have occurred in the Wash Estuary, UK, since 2008. A previous study linked the mortalities to a novel genotype of , with a strong correlation between cockle moribundity and the presence of . Here, we characterize a novel iridovirus, identified by chance during metagenomic sequencing of a gradient purification of cells, with the presence also correlated to cockle moribundity.
View Article and Find Full Text PDFMicrob Genom
September 2025
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan, ROC.
remains a leading respiratory pathogen for children and the elderly. In Taiwan, a national PCV13 catch-up vaccination programme for children began in March 2013. This study investigates the population structure and antimicrobial profiles of pneumococcal isolates in Taiwan from 2006 to 2022.
View Article and Find Full Text PDFJ Infect Dis
September 2025
Biological Sciences, Sunnybrook Research Institute, Sunnybrook Hospital, Toronto, Ontario, Canada.
Background: Tecovirimat (TPOXX) is an antiviral authorized for the treatment of mpox infections in Canada, but recent clinical trials found it has no impact on symptom duration.
Methods: We conducted a prospective cohort study of individuals diagnosed with mpox in Toronto, Canada. Skin lesion swabs were collected weekly to quantify infectious monkeypox virus (MPXV) shedding through cell culture.
Background: A significant surge in pertussis cases since early 2023 has raised serious public health concerns. To investigate the potential mechanisms contributing to this increased prevalence, we collected throat swab specimens from children exhibiting pertussis symptoms and conducted detailed molecular characterization.
Methods: All Bordetella pertussis (B.
PLoS One
September 2025
Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Background: Disulfidptosis, a novel cellular death manner, has yet to be fully explored within the context of pulmonary arterial hypertension (PAH). This study aims to identify genes implicated in PAH that are involved in disulfidptosis.
Method: Based on data from the GEO database, this study employed co-expression analysis, Weighted Gene Co-Expression Network Analysis (WGCNA), hub gene identification, and Gene Set Enrichment Analysis (GSEA) to uncover genes associated with PAH and disulfidptosis.