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Loss of life expectancy (LLE) was used to evaluate and quantitate the health risk caused by carcinogen and non-carcinogen pollutants, and was proposed as a new method to compare the environmental health risk of different pollutants. The environmental health risks exposed by 6 major environmental pollutants in China, i.e., arsenic, DDTs, BaP, lead, cadmium and mercury, were evaluated and compared by using LLE. The LLE caused by carcinogen pollutants such as arsenic, DDTs and BaP are 3.6 d, 2.2 d and 12.1 d respectively, while the corresponding values caused by non-carcinogen pollutants such as lead,mercury and cadmium are 1.1 d, 1.7 d and 5.8 d respectively. Based on the studies published before, the rank of the health risk of the selected six environmental pollutants is BaP > cadmium > arsenic > DDTs > mercury > lead. The results reveal that the LLE can be utilized as a new index to evaluate and quantitate the health risk, and the environmental health risk caused by carcinogen and non-carcinogen pollutants can be compared within an unitive criterion by LLE.
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Clin J Am Soc Nephrol
September 2025
University College London Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.
Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.
Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.
Clin J Am Soc Nephrol
September 2025
Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland USA.
Socioeconomic, environmental and lifestyle factors shape kidney health. Among the social determinants of health, access to healthy foods is particularly significant. As a basic need, food is integral to an individual's identity, culture, and health.
View Article and Find Full Text PDFJ Clin Invest
September 2025
The University of Texas at Austin, Austin, United States of America.
Background: Following SARS-CoV-2 infection, ~10-35% of COVID-19 patients experience long COVID (LC), in which debilitating symptoms persist for at least three months. Elucidating biologic underpinnings of LC could identify therapeutic opportunities.
Methods: We utilized machine learning methods on biologic analytes provided over 12-months after hospital discharge from >500 COVID-19 patients in the IMPACC cohort to identify a multi-omics "recovery factor", trained on patient-reported physical function survey scores.
Nutr Cancer
September 2025
Department of Kinesiology and Nutrition, University of Illinois Chicago, Iowa City, IL, USA.
Increased adiposity and chronic psychosocial stress (CPS) are plausible modifiable contributors of the recent increase in early-onset colorectal cancer (EOCRC). We conducted an 8-week randomized controlled pilot trial evaluating the feasibility and acceptability of time restricted eating (TRE) (daily ad libitum eating between 12-8pm) and Mindfulness ("Mindfulness for Beginners" course from the Calm app) among young adults. Participants were randomized to the following groups: TRE ( = 10); Mindfulness ( = 11); TRE & Mindfulness ( = 11); or Control ( = 11).
View Article and Find Full Text PDFSoc Work Public Health
September 2025
Department of Healthcare Management, Çankırı Karatekin University, Çankırı, Türkiye.
This study investigates socioeconomic disparities in chronic respiratory diseases and the factors contributing to these inequalities, using data from the 2019 Turkish Health Survey. Multivariate logistic regression and Oaxaca-Blinder decomposition analyses reveal that 13.10% of adults aged 25 and older in Turkey suffer from chronic respiratory diseases, with a significantly higher prevalence among lower socioeconomic status (SES) individuals.
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