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Objective: The purpose of this study was to investigate the association between peripheral calcification in thyroid nodules detected on ultrasonography and thyroid malignancy.
Methods: We retrospectively analyzed the ultrasonographic features of 65 pathologically proven thyroid lesions showing peripheral calcification for their correlation with histopathologic results. The following ultrasonographic parameters were assessed for each nodule: size (maximal dimension), shape (anteroposterior dimension/transverse dimension ratio), internal echogenicity (hypoechoic, isoechoic, hyperechoic, or invisible), halo sign (present or absent), type of calcification (stippled, curvilinear/smooth margin, or curvilinear/irregular margin), and extent of calcification (arc or rim).
Results: Twelve (18.5%) of 65 thyroid nodules with peripheral calcification were malignant, and 53 (81.5%) were benign. Patient demographics (age and sex) and ultrasonographic features of the nodules (size, shape, internal echogenicity, halo sign, and type and extent of calcification) did not show any significant differences between benign and malignant groups.
Conclusions: The relatively high prevalence of malignancy and no reliable criterion for malignancy in thyroid nodules with peripheral calcification indicate that fine-needle aspiration or careful ultrasonographic follow-up may be warranted in these cases.
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http://dx.doi.org/10.7863/jum.2007.26.10.1349 | DOI Listing |
Rev Clin Esp (Barc)
September 2025
Servicio de Medicina Interna, Hospital Marqués de Valdecilla, Santander, Spain; Departamento de Medicina y Psiquiatría, Universidad de Cantabria, Instituto de Investigación de Valdecilla, IDIVAL, Santander, Spain.
Introduction: Aortic arch calcification (AAC) is an underestimated marker of cardiovascular risk, associated with a higher incidence of major cardiovascular events and mortality.
Materials And Methods: This retrospective, descriptive study included 292 patients admitted in May 2021 to the Internal Medicine Department of Marqués de Valdecilla University Hospital. The presence of AAC was assessed via chest X-rays, alongside clinical data, risk factors, and previous and 12-month cardiovascular events.
Vascular
September 2025
Department of Vascular Surgery, Heart Vascular and Thoracic Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
ObjectiveCombined iliofemoral endarterectomy and iliac stenting (IFE + S) is a proven surgical approach for TransAtlantic Inter-society Consensus (TASC) C and D aortoiliac occlusive disease (AIOD). Iliac stenting alone (ISA) may be an attractive, minimally invasive option in select cases; however, untreated moderate-to-severe common femoral disease may threaten iliac stent patency and limit symptom improvement. This study evaluates the mid-term patency rates after IFE + S versus ISA for TASC C and D AIOD as well as the rate of interval femoral endarterectomies in those who underwent ISA.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Medical Imaging Center, Affiliated Hospital of Qinghai University, Xining, Qinghai, China.
Objective: To investigate the correlation between the changes of peripheral carotid fat density (PFD), the occurrence of acute cerebral ischemia events and the characteristics of different dangerous plaques.
Methods: A retrospective analysis was performed on patients diagnosed with carotid plaque by head and neck CTA in the Affiliated Hospital of Qinghai University from January 2021 to March 2023. All patients received head magnetic plain scan, DWI and high resolution vascular wall imaging (MR HR-VWI).
World J Gastroenterol
August 2025
Department of Hepatology, General Hospital Dr. Manuel Gea Gonzalez, Mexico City 14080, Mexico.
Endocrine disorders frequently lead to metabolic disturbances that significantly affect liver function. Understanding the complex interplay between hormonal imbalances and liver dysfunction is essential for advancing targeted therapeutic strategies. This comprehensive review explores the pathophysiological mechanisms linking major endocrine disorders to liver disease, with a focus on the roles of the thyroid, parathyroid, pancreas, adrenal glands, and sex hormones.
View Article and Find Full Text PDFPort J Card Thorac Vasc Surg
August 2025
Department of Angiology and Vascular Surgery, Coimbra Local Health Unit, Coimbra, Portugal.
Aim: Diabetes Mellitus is one of the main factors for peripheral arterial disease (PAD), while also being associated with medial arterial calcification, thus limiting the use of the ankle-brachial index. Pedal acceleration time (PAT), has emerged as a diagnostic alternative, by measuring the systolic acceleration in the arteries of the foot, with higher PAT values corresponding to a worse prognosis and with the literature suggesting a cut-off of 180 ms as a predictor of wound healing. We aimed to confirm whether we could use PAT to predict wound healing, need for revascularization and amputation in diabetic patients and whether this cut-off was valid in our population.
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