Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
We present a new analysis and visualization method for studying the functional relationship between the pulse morphology of pressure signals and time or signal metrics such as heart rate, pulse pressure, and means of pressure signals, such as arterial blood pressure and central venous pressure. The pulse morphology is known to contain potentially useful clinical information, but it is difficult to study in the time domain without the aid of a tool such as the method we present here. The primary components of the method are established signal processing techniques, nonparametric regression, and an automatic beat detection algorithm. Some of the insights that can be gained from this are demonstrated through the analysis of intracranial pressure signals acquired from patients with traumatic brain injuries. The analysis indicates the point of transition from low-pressure morphology consisting of three distinct peaks to a high-pressure morphology consisting of a single peak. In addition, we demonstrate how the analysis can reveal distinctions in the relationship between morphology and several signal metrics for different patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1109/TBME.2007.892918 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Minimizing Ionic Interference: An APCI-MS Strategy for Real-Time Reaction Monitoring in Ionic Liquids.
J Mass Spectrom
October 2025
Department of Chemistry and Technology of Drugs, "Sapienza" University of Rome, Rome, Italy.
Ionic liquids (ILs) are a class of organic salts with melting points below 100°C. Owing to their unique chemical and physical properties, they are used as solvents and catalysts in various chemical transformations, progressively replacing common volatile organic solvents (VOCs) in green synthetic applications. However, their intrinsic ionic nature can restrict the use of mass spectrometric techniques to monitor the time progress of a reaction occurring in an IL medium, thus preventing one from following the formation of the reaction products or intercepting the reaction intermediates.
View Article and Find Full Text PDFAnterior-posterior and medial-lateral balance metrics are unchanged when two-dimensional pseudorandom motion perturbations are provided in semicircular canal coordinates.
Front Neurol
August 2025
Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Introduction: External continuous perturbations using a motion platform have been developed by employing either sum-of-sines (SoS) or a pseudorandom ternary sequence (PRTS) of numbers to quantify body sway evoked in the medial-lateral (ML) or anterior-posterior (AP) directions, which ultimately helps understand the human postural control system. These stimuli have been provided via pitch tilts of the motion platform for evaluations of AP balance responses or roll tilts for ML balance responses. However, little is known about whether a healthy postural control system responds to 2-dimensional (2D) perturbations similarly when the perturbation stimuli are provided in semicircular canal coordinates (i.
View Article and Find Full Text PDFReal-World Safety of Esketamine Nasal Spray: A Comprehensive Analysis Almost 5 Years After First Approval.
Am J Psychiatry
September 2025
School of Psychology, Faculty of Science, University of Sydney, and Australia Brain and Mind Centre, University of Sydney, Sydney, Australia.
Objective: The objective of this study was to comprehensively examine the real-world safety of esketamine using 58 months of postapproval data in the United States.
Methods: U.S.
Myogenic induced adipose-derived stem cells sheets combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) for stress urinary incontinence treatment.
J Mol Histol
September 2025
Department of Urology, Yantai Yuhuangding Hospital, Qingdao University, No. 20 East Yuhuangding Road, Yantai, 264000, Shandong, China.
The stress urinary incontinence (SUI) is a difficulty in urology and current sub-urethral sling treatments are associated with inflamation and recurrence. In this study, we developed a novel tissue-engineered sling with myogenic induced adiposederived stem cells (MI-ADSCs) sheets induced by 5-Aza and combined with electrospun scaffolds of silk fibroin and poly(lactide-co-glycolide) (SF/PLGA) for the treatment of stress urinary incontinence. MI-ADSCs increased α-SMA, MyoD and Desmin the mRNA and protein expression.
View Article and Find Full Text PDFThermosensitive transient receptor potential channel proteins: Emerging targets for acute lung injury: A review.
Int J Biol Macromol
September 2025
College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. Electronic address:
The thermosensitive transient receptor potential (Thermo-TRP) channel proteins comprise TRPA1, TRPV1-V4, and TRPM8. TRP channels are mainly situated on cellular surfaces and react to a range of external factors, including heat, cold, acidity, osmotic pressure, chemical signals, and flavors, as well as intracellular signals such as Ca, Na, and cytokines. The thermo-TRP channels are associated with many physiological signal pathways, with their distinct molecular structure making them promising drug targets for respiratory diseases.
View Article and Find Full Text PDF