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Computed tomography (CT)-guided thoracic sympathetic blockade with ethanol was performed while monitoring sympathetic nerve activity, with an alternating current (AC) galvanic skin reflex (GSR) monitor, in a patient with palmar hyperhidrosis in whom endoscopic thoracic sympathectomy was impossible because of pleural adhesion. Sweating was suppressed after the thoracic sympathetic blockade, and the monitor showed a significant increase in skin resistance. The effect of sympathetic blockade could be evaluated directly and in real time using a GSR monitor.
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http://dx.doi.org/10.1007/s00540-007-0517-y | DOI Listing |
Br J Anaesth
September 2025
MSk Lab, Imperial College London, London, UK; Theatres and Anaesthetics, Imperial College Healthcare NHS Trust, London, UK. Electronic address:
Background: The mechanisms contributing to epidural-related maternal hyperthermia remain unclear. One explanation is that blockade of cholinergic sympathetic nerves prevents active vasodilation and sweating. However, it is not known how labour epidural analgesia affects cutaneous sympathetic function.
View Article and Find Full Text PDFCardiol Rev
September 2025
Departments of Cardiology and Medicine, Westchester Medical Center and New York Medical College, Valhalla, NY.
Sepsis remains a leading cause of critical illness and mortality worldwide, driven by a dysregulated host response to infection and often complicated by persistent tachycardia and cardiovascular dysfunction. Increasing evidence implicates excessive sympathetic activation as a contributor to sepsis-related hemodynamic instability and myocardial injury, prompting growing interest in the use of β-adrenergic blockade as a therapeutic adjunct. This review synthesizes current data on the safety and efficacy of short-acting, cardioselective β-blockers (BBs), particularly esmolol and landiolol, in septic shock.
View Article and Find Full Text PDFHeartRhythm Case Rep
August 2025
Department of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands.
Cureus
August 2025
Anesthesiology, Maharani Laxmi Bai Medical College, Jhansi, IND.
Background Preeclampsia is a serious hypertensive disorder of pregnancy characterized by multi-organ dysfunction and often necessitates cesarean delivery. While spinal anesthesia is preferred for cesarean sections, lumbar subarachnoid block may result in significant hypotension due to extensive sympathetic blockade. Thoracic spinal anesthesia has emerged as a potential alternative with better hemodynamic control.
View Article and Find Full Text PDFMol Cell Neurosci
August 2025
Department of Pharmacy, Ludwig-Maximilians-Universitat, Munchen, Munich, Germany.
Traumatic brain injury is not constrained only to the brain but delayed secondary events disturb the end organ functioning via intense response of three homeostatic mechanisms such as sympathetic activity, inflammation, and immunosuppression. Current study involved weight drop model to induce TBI in Swiss albino mice. Eprosartan was administered orally after 30-45 min post injury to mice in 0.
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