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http://dx.doi.org/10.1016/j.vaccine.2007.02.064 | DOI Listing |
Cureus
August 2025
Department of Anesthesiology and Intensive Care Medicine, Akita University Graduate School of Medicine, Akita, JPN.
Local anesthetics (LAs) are widely used to relieve surgical pain. Pure amide-type LAs rarely cause allergic reactions. Here, we present a case of anaphylaxis induced by multiple pure amide agents.
View Article and Find Full Text PDFCureus
August 2025
Emergency Medicine, Stockport NHS Foundation Trust, Stockport, GBR.
Kounis syndrome, also known as allergic myocardial infarction, is a rare but potentially life-threatening condition in which acute coronary events are triggered by an allergic reaction. The pathophysiology involves mast cell degranulation and the release of inflammatory mediators such as histamine, leukotrienes, and platelet-activating factor, leading to coronary vasospasm, myocardial ischemia, or infarction. We present the case of a female patient in her 80s with no prior history of coronary artery disease who developed anaphylaxis shortly after intravenous administration of co-amoxiclav in the emergency department.
View Article and Find Full Text PDFAnn Hematol
September 2025
Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.
In a subset of patients with systemic mastocytosis (SM), an associated hematologic neoplasm (AHN) is identified. Most AHN are myeloid neoplasms, whereas lymphoid neoplasms are uncommon. We report on a 70-year-old female patient with bone marrow mastocytosis (BMM) associated with primary cutaneous follicle center lymphoma (PCFCL).
View Article and Find Full Text PDFBMJ Case Rep
September 2025
Department of Cardiology, University of Rochester Medical Center, Rochester, New York, USA.
We present a case of a middle-aged woman with an extensive history of adverse reactions to iodinated contrast media (ICM) despite premedication. The patient presented from an outside hospital with an ST elevation myocardial infarction in the inferior and anterior leads. She received thrombolytics and was transferred to our hospital.
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July 2025
Allergy and Immunology, Keesler Medical Center, Biloxi, USA.
We present the case of a 33-year-old active-duty male with a history of anaphylaxis following fish ingestion, allergic rhinoconjunctivitis, and multiple environmental and food allergies confirmed with serum-specific IgE testing. This report discusses the patient's clinical presentation, diagnostic evaluation, and management plan, including allergen avoidance, epinephrine use, environmental control strategies, and a case of unexpected severe anaphylaxis despite low serum-specific IgE levels. Military service requires stringent physical capabilities, and deployment requirements add an additional layer of complexity to the outlook of this case.
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