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In this study we assessed the incidence of voiding dysfunction in women 6 months after undergoing a tension-free vaginal tape (TVT) procedure. Logistic regression was then used to look for significantly associated factors from a range of patient, urodynamic and surgical variables. From a group of 267 women we identified 22 (8%) who needed to perform daily intermittent self-catheterisation (ISC) as a result of the TVT surgery. When potential predictive factors were examined individually there were three that appeared to be associated with the need to use ISC: menopausal status,previous incontinence surgery and the centile score for average voiding flow rate (as derived from a volume--flow rate nomogram). Following multivariate logistic regression this flow rate centile score showed the strongest association with post-TVT voiding dysfunction, the likelihood of needing ISC increasing as the centile score fell. This factor has not previously been described but is readily assessed pre-operatively and may be useful in case selection for TVT.
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http://dx.doi.org/10.1007/s00192-007-0324-x | DOI Listing |
Cureus
August 2025
General Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.
Many patients with injuries to their central nervous system, especially those who have had a stroke or a spinal cord injury, have neurogenic voiding dysfunction. It happens when patients can't control their bladder voluntarily, which can make them feel urgency, experience leaks, or have trouble emptying their bladder. If not treated right away, it can cause infections, damage to the bladder, or even kidney problems over time.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
July 2025
Dongzhimen Hospital, Beijing University of Chinese Medicine Beijing 100700, China.
This study employed bioinformatics to screen the feature genes related to efferocytosis in diabetic kidney disease(DKD) and explores traditional Chinese medicine(TCM) regulating these feature genes. The GSE96804 and GSE30528 datasets were integrated as the training set, and the intersection of differentially expressed genes and efferocytosis-related genes(ERGs) was identified as DKD-ERGs. Subsequently, correlation analysis, protein-protein interaction(PPI) network construction, enrichment analysis, and immune infiltration analysis were performed.
View Article and Find Full Text PDFJ Biomed Mater Res A
September 2025
Department of Urology, China Rehabilitation Research Center, Beijing Boai Hospital, School of Rehabilitation of Capital Medical University, Beijing, China.
This study investigated the therapeutic effects of a composite small intestinal submucosa decellularized extracellular matrix/hyaluronic acid (HA)-incorporated thermosensitive hydrogel (HA-Gel) on interstitial cystitis (IC) in rats. The HA-Gel was fabricated using rabbit small intestinal submucosa-derived extracellular matrix as a thermosensitive scaffold combined with HA, and an IC rat model was established using the UPK3A65-84 peptide. Rats were divided into five groups: IC group, IC + HA group, IC + Gel group, IC + HA-Gel group, and a non-modeled control group.
View Article and Find Full Text PDFFolia Med Cracov
December 2024
Department of Gerontology and Geriatric Nursing, School of Health Sciences, Medical University of Silesia, Katowice, Poland.
Introduction: Prostate benign hyperplasia affects a significant number of men over 50 years, often causing symptoms in the lower urinary tract. While, prostate cancer is the most common cancer in recent decades.
Aim: The aim of the study was assessment of the level of illness acceptance, sexual, and urinary disorders among men with prostate cancer or benign prostatic hyperplasia.
J Muscle Res Cell Motil
September 2025
Department of Comparative Biosciences, University of Wisconsin-Madison, 2015 Linden Dr, Madison, WI, 53706, USA.
In the lower urinary tract, coordinated function between the bladder and urethra is essential for normal micturition, requiring smooth muscle contraction and relaxation in a tightly regulated cycle. During the bladder filling phase, the bladder remains relaxed while the urethra stays contracted to prevent leakage. During voiding, this coordination reverses, and the bladder contracts to expel urine while the relaxed urethra allows urine flow.
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