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Objective: To investigate the feasibility and safety of intraoral submandibular gland excision.
Methods: Analyze the relationship between the external maxillary artery and submandibular gland, and offer a reliable anatomical base for 10 cases of intraoral submandibular gland excision, including 8 cases of chronic sialadenitis, 1 case of pleomorphic adenoma and 1 case of cyst of submandibular gland.
Results: The external maxillary artery went across the surface of gland submandibular, and its branches provided nutrition for the gland in most cases. The results of 10 cases intraoral submandibular gland excision were effective and satisfied, without major complications. The average time of operation was 50 minutes and the average hemorrhage of operation was 60 ml.
Conclusion: Intraoral submandibular gland excision is safe and feasible for chronic sialadenitis and cyst of submandibular gland and some of benign tumor submandibular gland as long as indications strictly controlled and the external maxillary artery well coped with.
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Oral Maxillofac Surg
September 2025
Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Shinmachi 2-5-1, Hirakata-city, Osaka, Japan.
Purpose: For submandibular gland resection, conventional surgery with the naked eye remains the standard. With its excellent automatic focus and high magnification, the ORBEYE 3D exoscope enables precise submandibular gland resection with less stress. Therefore, we aimed to examine the usefulness of the exoscope in submandibular gland resection.
View Article and Find Full Text PDFSaudi Dent J
September 2025
Oral Biology Department, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
To compare the efficacy of using bone marrow mesenchymal stem cell (BM-MSC) exosomes and injectable platelet rich fibrin (i-PRF) on the submandibular salivary glands (SMGs) of aged albino rats in restoring salivary gland structure and function. A total of 40 healthy male albino rats were used, two for obtaining the BM-MSCs, 10 for i-PRF preparation and seven adult rats (6-8 months old) represented the control group (Group 1). The remaining 21 rats were aged (18-20 months old) and divided into three groups of seven rats each; (Group 2): received no treatment, (Group 3): each rat received a single intraglandular injection of BM-MSC exosomes (50 μg/kg/dose suspended in 0.
View Article and Find Full Text PDFJ Oral Pathol Med
September 2025
Department of Pediatric Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Background: Oral and plunging ranulas require effective treatment strategies to minimize recurrence; yet no consensus exists on the most effective approach.
Objectives: This systematic review evaluated several treatments for the recurrence of oral and plunging ranulas.
Methodology: A comprehensive search was conducted in five bibliographic databases and gray literature.
Head Neck Pathol
September 2025
Department of Laboratory Medicine and Pathology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Myoepithelial carcinoma (MECA) is a malignant neoplasm composed exclusively of myoepithelial cells and accounts for less than 1% of all salivary gland tumors. Its diagnosis is often challenging due to histologic overlaps with benign lesions and its variable morphologic presentation. Although molecular profiling has emerged as a valuable tool in salivary gland tumor classification, the genetic landscape of MECA remains incompletely defined.
View Article and Find Full Text PDFJ Nutr Biochem
September 2025
Multicentric Postgraduate Program in Physiological Sciences, SBFis, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Department of Basic Sciences, São Paulo State University (UNESP), School of Dentistry, Araçatuba, SP, Brazil; Postgraduate Program in Sciences, Pedi
Studies indicate that dietary patterns influence the function and redox balance of salivary glands. This study examined the effects of intermittent fasting (IF) on the function, histological structure, and redox balance of the salivary glands. Twenty 12-weeks-old male Wistar rats were randomized into two groups: ad libitum (AL), with continuous access to water and chow, and IF, subjected to 24-hour fasting on alternate days for 12 weeks.
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