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Appropriate extent of lymph node dissection in patients with muscle-invasive gallbladder cancer.

HPB (Oxford)

August 2025

Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, Republic of Korea. Electronic address:

Background: The appropriate extent of lymph node dissection has not yet been standardized in muscle-invasive gallbladder cancer.

Methods: Patients who underwent surgery, and were histologically diagnosed with muscle-invasive gallbladder cancer were included. Patients were classified as having Na, Nb, or Nc disease if their nodal metastases were limited to the porta hepatis and extended to the posterosuperior pancreatic head lymph nodes (PSPLNs), nodes along the celiac axis, or superior mesenteric vessels.

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