98%
921
2 minutes
20
Gait analysis plays an important role in the assessment of neurological function in many disease models. In this review, we focus on the newly developed CatWalk system for gait analysis. CatWalk was originally developed as a tool to enhance assessment of functional outcome in spinal cord injury (SCI) models. Although it is also of value in models of among others (neuropathic) pain and peripheral nerve damage, we will limit ourselves to its use in SCI models in this review. The system is positioned against well-established locomotor function tests, and it is indicated how CatWalk can enhance the usefulness of such tests. Development of the system started with the idea that it should enable objective assessment of coordination, and powerful measures of coordination are nowadays included in the analysis options provided by CatWalk. Therefore, a major part of this review is devoted to the history and meaning of these coordination measures.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1089/neu.2006.23.537 | DOI Listing |
J Biomech
August 2025
Lampe Joint Department of Biomedical Engineering, UNC Chapel Hill & NC State University, Chapel Hill, NC, USA. Electronic address:
Walking is essential for maintaining independence and quality of life, yet aging may impair the neuromuscular function required for stable gait over time. This study sought to quantify age-related differences in step-to-step control during prolonged walking using detrended fluctuation analysis (DFA). We hypothesized that step-to-step changes in step length and step width would exhibit reduced temporal persistence over time, with more pronounced effects in older than in younger adults.
View Article and Find Full Text PDFInterv Neuroradiol
September 2025
Department of Neurosurgery, Albany Medical Center, Albany, NY, USA.
ObjectiveRandomized trials will ultimately determine whether stand-alone middle meningeal artery embolization (MMAE) is effective in preventing the recurrence of chronic subdural hematoma (cSDH). We therefore characterized in-hospital complications, length of stay, and discharge disposition among adults undergoing stand-alone MMAE for non-traumatic cSDH in the United States.MethodsWe conducted a retrospective cohort analysis using the National Inpatient Sample (2016-2022) to identify adult patients (≥18 years) with a primary diagnosis of nontraumatic cSDH.
View Article and Find Full Text PDFIEEE Internet Things J
August 2025
Geometric Media Lab, School of Arts, Media and Engineering and School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85281 USA.
Human gait analysis with wearable sensors has been widely used in various applications, such as daily life healthcare, rehabilitation, physical therapy, and clinical diagnostics and monitoring. In particular, ground reaction force (GRF) provides critical information about how the body interacts with the ground during locomotion. Although instrumented treadmills have been widely used as the gold standard for measuring GRF during walking, their lack of portability and high cost make them impractical for many applications.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Background: Gait deficits and leg spasticity are frequent symptoms in Primary and Secondary Progressive Multiple Sclerosis (PPMS and SPMS). Transcutaneous spinal cord stimulation (tSCS) may alleviate these symptoms through the reduction of spinal hyperexcitability. We conducted a single-center, randomized, sham-controlled clinical crossover study (German Clinical Trials Register: DRKS00023357, https://www.
View Article and Find Full Text PDFJ Exerc Rehabil
August 2025
Faculty of Care and Rehabilitation, Seijoh University, Toukai, Japan.
Load asymmetry in the lower limbs of patients with hip fracture is associated with decreased gait ability, impaired balance, and increased risk of fall. The modified sit-to-stand (STS), which combines positioning the foot behind with chair seat elevation, facilitates loading on the affected limb. This study aimed to investigate lower limb load asymmetry during STS and walking in patients with hip fracture after modified STS training.
View Article and Find Full Text PDF