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Lead and Cadium as the key elements influencing human genetic health were selectively determined in the present paper. In the area of metal elements determination in body fluid, most samples used in the study are blood, plasma and saliva. No literature about genetic fluid determination has been found so far. In the present paper the preparation of samples, volume of samples, and determination parameters were investigated. An easy reliable method of determining lead and cadium in semen and liquor follicle is established. The recoveries of lead are 99.0%-118% and the recoveries of cadium are 96.3%-109%. The determination limit of lead is 0.8 microg x L(-1) and the determination limit of cadium is 0.05 microg x L(-1). The relative standard deviations (RSD)(n = 5) are 3.74%-8.54%.
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Biosensors (Basel)
August 2025
Biomedical Engineering Programme, School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China.
Exosomes are membranous vesicles that play a crucial role as intercellular messengers. Cells secrete exosomes, which can be found in a variety of bodily fluids such as amniotic fluid, semen, breast milk, tears, saliva, urine, blood, bile, ascites, and cerebrospinal fluid. Exosomes have a distinct bilipid protein structure and can be as small as 30-150 nm in diameter.
View Article and Find Full Text PDFBiomedicines
February 2025
Department of Obstetrics and Gynecology, RAK College of Medical Sciences (RAKCOMS), RAK Medical & Health Sciences University (RAKMHSU), Ras Al-Khaimah P.O. Box 11172, United Arab Emirates.
Caffeine is commonly used to excess by the general public, and most pregnant women drink caffeine on a daily basis, which can become a habit. Maternal caffeine intake during pregnancy is associated with severe gestational outcomes. Due to its lipophilic nature, caffeine can cross the blood-brain barrier, placental barrier, and even amniotic fluid.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
February 2025
Genetics Center of Obstetrics and Gynecology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China.
To analyze the prenatal diagnostic results in families with monogenic diseases and the mutation origins in affected children from families with reproductive history of children with recurrent mutations (DNMs). This study was a cross-sectional study. A total of 41 cases with adverse pregnancy history of monogenic diseases who underwent genetic counseling and prenatal diagnosis from January 2021 to December 2023 at the Obstetrics and Gynecology Hospital of Fudan University were included.
View Article and Find Full Text PDFCureus
November 2024
Forensic Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.