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An unusual sentinel node location in a patient with penile carcinoma is described. The preoperative lymphoscintigram showed a prepubic sentinel node. The node could be harvested during surgery. This case illustrates one of the advantages of lymphatic mapping in penile carcinoma: preoperative lymphoscintigraphy can identify lymph nodes outside the usual nodal basins.
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http://dx.doi.org/10.1097/01.rlu.0000178000.25105.e0 | DOI Listing |
J Surg Oncol
September 2025
Cumming School of Medicine, University of Calgary, Calgary, Canada.
Superparamagnetic iron oxide (SPIO) tracer is a potential option for sentinel lymph node biopsy (SLNB), though its application in melanoma remains minimally explored. This systematic review evaluated the use of SPIO tracer compared to the standard approach for SLNB in melanoma. SPIO demonstrated comparable efficacy and detection rate to the gold standard, with a sensitivity of 94%.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Objective: The risk of lymph node metastasis significantly influences the choice of surgical strategy for patients with early-stage endometrial cancer. While sentinel lymph node dissection can be considered in clinically early-stage endometrial cancer, lymph node evaluation might be omitted in patients with very low risk of lymph node metastasis. This study aims to develop a predicting model for lymph node metastasis in these patients, identifying potential metastases as thoroughly as possible to provide clinicians with a preoperative reference that helps in decisions about surgical procedures and treatments.
View Article and Find Full Text PDFCureus
August 2025
Medicine, Academy of Silesia, Katowice, POL.
We present the case of a 45-year-old Caucasian woman diagnosed with synchronous bicentric breast cancer of differing molecular phenotypes in the same breast. The first tumor, an invasive ductal carcinoma (G1), was estrogen and progesterone receptor-positive and HER2-negative, with a low proliferative index (Ki67 10%). A second lesion, located in a different quadrant and appearing within weeks after biopsy, exhibited a triple-negative phenotype and a higher proliferative index (Ki67 30%).
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August 2025
Plastic and Reconstructive Surgery, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, GBR.
Objectives: This study evaluates the management of paediatric melanoma at a tertiary centre, comparing clinical practices with international guidelines from the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) and the National Comprehensive Cancer Network (NCCN) to highlight real-world practices and make recommendations for future research priorities. The differences between conventional and Spitzoid melanomas were also explored in a subgroup analysis.
Background: Paediatric melanoma is rare and is most commonly caused by UV exposure or familial mutations.
Aim: This study explores the evolving landscape of gastrectomy procedures in Japan, based on nationwide surveys conducted in 2014 and 2021. It highlights changes in surgical approaches, including a growing focus on minimally invasive and function-preserving procedures, as well as the increasing consideration of postoperative quality of life (QOL).
Methods: Two nationwide questionnaire surveys were conducted in 2014 and 2021, targeting members of the Japanese Society for Gastro-surgical Pathophysiology.