98%
921
2 minutes
20
Natural eCG consists of as much as 45% carbohydrate side chains. The present paper deals with the analysis of the roles of the N- and O-linked saccharides of this hormone in the different steps of its activity and its possible replacement by recombinant eCG expressed in baculovirus-insect cell systems.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1051/rnd:2005018 | DOI Listing |
Neurology
October 2025
Neurology, Epilepsy and Movement Disorders Unit, Bambino Gesù Children's Hospital, IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies - EpiCARE, Rome, Italy.
Objectives: Neuronal ceroid lipofuscinosis type 3 (CLN3) is a rare lysosomal storage disorder characterized by progressive neurodegeneration. No disease-modifying treatments are currently available. Miglustat, a substrate reduction therapy, has shown preclinical efficacy in CLN3 models (conference abstract).
View Article and Find Full Text PDFGen Physiol Biophys
September 2025
Faculty of Exact and Natural Sciences, I. Javakhishvili Tbilisi State University, Tbilisi, Georgia.
In this study, both pure and calcium-containing complex liposomes made from DPPC phospholipids were investigated using calorimetric and spectrophotometric methods. Liposomes were prepared using a new technology in both water and a 20% glycerol aqueous solution. Glycerol allows drug-containing DPPC liposomes to penetrate the dermis of the skin through the epidermis.
View Article and Find Full Text PDFSupport Care Cancer
September 2025
Methodist Le Bonheur Healthcare, Department of Pharmacy, Memphis, TN, USA.
Purpose: Hypersensitivity reactions are a side effect of bleomycin. Test doses have been utilized to attempt to predict patients who would develop these reactions. Despite this, there is scant data available on whether these test doses actually predict the development of reactions.
View Article and Find Full Text PDFFood Chem X
August 2025
Division of Industrial Biotechnology, Department of Life Sciences, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Vegetable side streams are resulting non-edible by-products from vegetable processing. These side streams are a rich source of bioactive compounds and macromolecules. Despite their potential for high-value applications, these materials are frequently used in low-value applications or discarded, contributing to resource depletion and environmental concerns.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
College of Food Science, South China Agricultural University, Guangzhou 510642, China. Electronic address:
Sacha inchi shell extract (SISE), whose main active substance is a polysaccharide, has been reported to have hypotensive effects. Consequently, a novel acidic arabinogalactan, termed SISP, was isolated from SISE, and its efficacy in protecting vascular endothelial cells was investigated. SISP had a molecular weight of 57.
View Article and Find Full Text PDF