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Objective: Iatrogenic surgical injury to large blood vessels in the abdomen or pelvis is a rare adverse event but may be lethal. We present a new technique to repair serious vascular injury using a free graft of omentum or fascia as an overlay autogenous tissue (OAT) patch.
Methods: Repair to venous and arterial defects was made using an OAT patch of omentum or rectus abdominis sheath sutured through the patch and the adventitia of the injured vessel at four sites. The technique was tested in 33 repairs in an experimental sheep model.
Results: Thirty-three patch repairs were attempted and all were successfully completed. Twenty-one (64%) patches were controlled by the patch alone, and adjuvant local pressure was required in 12 (36%) cases.
Conclusion: We have demonstrated that an OAT patch can be used to control vascular injury in the experimental sheep model. This technique may be useful to all surgeons especially those operating in the pelvis where there may be restricted access to repair vascular injury.
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http://dx.doi.org/10.1016/j.ygyno.2004.05.012 | DOI Listing |
Eur J Orthop Surg Traumatol
September 2025
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Background: To analyze penetrating extremity injuries at a Scandinavian urban Level-1 trauma center regarding incidence, mechanism of injury, imaging approach and clinical outcome.
Methods: A retrospective study (2013-2016) of penetrating injuries to the extremities based on a Trauma Registry. Retrieved variables included patient demographics, injury characteristics, time to CT and 30-day morbidity.
JACC Cardiovasc Interv
September 2025
CVPath Institute, Gaithersburg, Maryland, USA; University of Maryland, School of Medicine, Baltimore, Maryland, USA. Electronic address:
Background: Effective modification of heavily calcified coronary lesions is critical for successful percutaneous coronary intervention (PCI). Intravascular lithotripsy (IVL), cutting balloons (CBs), and ultra-high-pressure balloons (UHBs) are used commonly, yet data comparing their effectiveness and safety for calcified lesion modification remain unavailable.
Objectives: The aim of this study was to compare the effects of IVL, a CB, and a UHB on calcified coronary lesions in human cadaveric arteries, focusing on calcium fracture formation and vascular injury.
J Thorac Cardiovasc Surg
September 2025
Department of Cardiovascular Surgery, Kanazawa University, Takaramachi 13-1 Kanazawa 920-8641, Japan.
Objective: To assess the production of nitric oxide and endothelin in off-pump coronary artery bypass grafting by comparing two techniques of internal thoracic artery preparation: skeletonized and pedicled without endothoracic fascia.
Methods: In this prospective, randomized clinical study, 40 patients undergoing off-pump coronary artery bypass grafting were randomized according to internal thoracic artery preparation technique into the skeletonized or pedicled (without endothoracic fascia) groups (n=20 each). Endothelial expression of CD31 was evaluated by means of immunohistochemistry and en-face immunofluorescence.
PLoS One
September 2025
Department of Cardiac Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Background: Cardiac ischemia reperfusion (I/R) injury is a serious consequence of reperfusion therapy for myocardial infarction (MI). Peptidylarginine deiminase 4 (PAD4) is a calcium-dependent enzyme that catalyzes the citrullination of proteins. In previous studies, PAD4 inhibition protected distinct organs from I/R injury by preventing the formation of neutrophil extracellular traps (NETs) and attenuating inflammatory responses.
View Article and Find Full Text PDFSud Med Ekspert
September 2025
Bureau of Forensic Medical Expertise, Saint-Petersburg, Russia.
Unlabelled: Forming wound canal is one of the main signs of gunshot wound. Its features are related to the following differential diagnostic signs: presence of gunshot wound, its intravitality, prescription, direction of projectile (bullet) movement, power of used weapon, etc.
Objective: To study the mechanisms of wound canal formation in gunshot injury, the pattern of damage to the biological tissues of its walls (mainly, blood vessels), the features of hemorrhages forming around it.