Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
A 70-year-old woman was examined because of increasing problems with cognition. She had a history of a cerebral shunt placed surgically 10 years previously. Introduction of Tc-99m DTPA directly into the ventricular cavity revealed good ventricular distribution, followed by progression downward, as though into a previous ventriculoperitoneal shunt. However, a chest radiograph revealed what appeared to be a shunt tube in the right atrium. Delayed lateral images showed activity in proximity to the vertebral column, indicating migration of tracer and cerebrospinal fluid into the dorsal and lumbar subarachnoid space.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00003072-200212000-00007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Utility of [Tc]Tc-tilmanocept, an immunosuppressive macrophage functional imaging agent in melanoma patients receiving checkpoint inhibitor treatment: a feasibility study.
Cancer Immunol Immunother
September 2025
Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, CHUV/UNIL, 1011, Lausanne, Switzerland.
Background: Immunotherapy is a mainstay in the treatment of patients with advanced melanoma. Yet, resistance mechanisms exist, and tumour-associated macrophages (TAMs), particularly the M2-like phenotype, are associated with poorer outcomes, with CD206 serving as their specific marker. We present the first human SPECT/CT study to visualize CD206 + TAMs in patients undergoing immunotherapy and compare the findings to clinical outcomes (NCT04663126).
View Article and Find Full Text PDFA novel method to quantify Dendrobium officinale polysaccharides in biological samples viaTc-labelling and radioHPGPC analysis.
Carbohydr Polym
November 2025
Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, 430030 Wuhan, PR China; Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, Wuhan 430022, PR China. Electronic address:
Natural polysaccharides are attracting increasing attention due to their excellent pharmacological properties and low toxicity. However, the clinical translation of these biomacromolecules has been hindered by a lack of pharmacokinetic studies. Polysaccharide labelling presents a promising method for performing pharmacokinetic investigations on polysaccharides.
View Article and Find Full Text PDFSynthesis and In Vitro Analysis of Dual-Functionalized Mesoporous Silica Nanoparticles for Targeted Theranosis of ER(+) Breast Cancer.
Drug Dev Res
August 2025
Institute of Nuclear Medicine and Allied Sciences, Defence Research and Development Organization, Delhi, India.
Mesoporous silica nanoparticles have been extensively utilized for targeted drug delivery; the drugs are encapsulated in the pores, while the surface can be modified to make the nanoparticles target-specific. The work presented here focuses on the development of multifunctional theranostic mesoporous silica nanoparticles with estrogen receptor-positive [ER(+)] breast cancer as the target. The surface of the nanoparticles was dually functionalized to make the nanoparticles target-specific using an estradiol derivative via a facile click reaction and to attach a Tc complexing agent (DTPA) for SPECT imaging.
View Article and Find Full Text PDFIntrathoracic Kidney Detected on DTPA Scan.
Indian J Nucl Med
June 2025
Department of Nuclear Medicine, Amrita School of Medicine (Amrita Vishwa Vidyapeetham - Deemed University), Faridabad, Haryana, India.
Intrathoracic kidney is very rare and has the lowest prevalence among all renal ectopias. We report the case of a 70-year-old male who was referred for diethylenetriaminepentaacetic acid (DTPA) scan as a part of presurgical work-up for a right renal mass. PriorUltrasonography abdomen incorrectly reported left kidney as normal in location.
View Article and Find Full Text PDFCT-free kidney single-photon emission computed tomography for glomerular filtration rate.
Sci Rep
July 2025
Department of Health Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 145 Gwanggyo-ro, Yeongtong- gu, Suwon-si, Gyeonggi-do, 16229, Republic of Korea.
This study explores an artificial intelligence-based approach to perform CT-free quantitative SPECT for kidney imaging using Tc-99 m DTPA, aiming to estimate glomerular filtration rate (GFR) without relying on CT. A total of 1000 SPECT/CT scans were used to train and test a deep-learning model that segments kidneys automatically based on synthetic attenuation maps (µ-maps) derived from SPECT alone. The model employed a residual U-Net with edge attention and was optimized using windowing-maximum normalization and a generalized Dice similarity loss function.
View Article and Find Full Text PDF