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http://dx.doi.org/10.1067/mhn.2002.123043 | DOI Listing |
Acad Psychiatry
September 2025
Te Whatu Ora, Christchurch, Canterbury, New Zealand.
Objective: Simulation-based learning replicates real clinical events to provide an interactive learning experience. This allows training doctors to develop skills to manage complex scenarios or emergencies in a safe and containing environment. Many house officers report a lack of confidence in managing emergencies on a psychiatric ward.
View Article and Find Full Text PDFEBioMedicine
September 2025
Albert B. Sabin Vaccine Institute, 2000 Pennsylvania Ave, NW, Suite 7000, Washington, DC, 20006, USA. Electronic address:
Background: Sudan virus and Marburg virus are high priority biological threat pathogens with fatality rates of 25-90%. Recent outbreaks in Uganda, Equatorial Guinea, and Rwanda between 2022 and 2025 emphasise the critical need for effective vaccines. The aim of this phase 1b study was to determine clinical safety, tolerability, and immunogenicity of these monovalent vaccines.
View Article and Find Full Text PDFJ Korean Neurosurg Soc
September 2025
Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Objective: To identify the ideal timing for resuming oral or injectable anticoagulants therapy after spontaneous intracranial hemorrhage (sICH).
Methods: We conducted a retrospective cohort study involving 90 patients from a tertiary hospital in Korea, between June 2000 and May 2022, who had experienced sICH while receiving anticoagulant therapy and who resumed treatment within six months. Exclusions were made for trauma-induced hemorrhages and early post-ictus fatalities.
Biomater Sci
September 2025
Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam.
Colorectal cancer is the second foremost cause of cancer-related fatalities, but it is currently missing an effective treatment. For researchers, the ability to monitor therapeutic nanoparticles of interest within a living animal using non-invasive observation tools has been a futuristic idea for a long time. In this work, a multifunctional magnetic nanotheranostic functionalized with Cyanine 5.
View Article and Find Full Text PDFNeurodegener Dis Manag
August 2025
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran.
Introduction: There are a few therapeutic approaches for Amyotrophic Lateral Sclerosis (ALS) which can only slow down or stop the disease progression for a limited period of time. Since it has been proven that Mesenchymal Stromal Cells (MSCs) produce neurotrophic factors and have some neuroprotective effects, stem cell therapy has been proposed as an alternative or add-on treatment for ALS patients.
Method & Material: In this open-label clinical trial, two-repeated dose of 60 million GMP compliant Wharton's Jelly-derived Mesenchymal Stromal Cells (WJ-MSCs) were transplanted intrathecally (#6 patients) or intravenously (#6 patients) twice with a 3-month interval.